Publications

2018

  • Chouhan, B. P. S.Maimaiti, S.; Gade, M.; Laurino P.* Rossmann-fold Methyltransferases: taking a 'beta-turn' around their cofactor S-Adenosylmethionine. Future of Biochemistry special Issue of ACS Biochemistry, 2019, 58, 166-170.

2017 or earlier

  • Laurino P., Tawfik D. S. Spontaneous Emergence of S-Adenosylmethionine and the Evolution of Methylation. Angew Chem Int Ed Engl. 2017, 56, 343-345. This article has been recommended in F1000Prime as being of special significance in its field.

  • Goldenzweig, A.; Goldsmith, M.; Hill, S. E.; Gertman, O.; Laurino, P.; Ashani, Y.; Dym, O.; Unger, T.; Albeck, S.; Prilusky, J.; Lieberman, R. L.; Aharoni, A.; Silman, I.; Sussman, J. L.; Tawfik, D. S.; Fleishman S. J. "Automated computational design of human enzymes for high bacterial expression and stability". Mol Cell 2016, 63, 337-346.

  • Laurino, P.; Rockah-Shmuel, L.; Tawfik D. S. “Engineering and directed evolution of DNA methyltransferases” Adv Exp Med Biol 2016, 945, 491-509

  • Laurino, P.; Tóth-Petróczy, A.; Meana-Pañeda R.; Lin W.; Truhlar D. G.; Tawfik, D. S. “An ancient fingerprint of coevolution of the Rossmann fold and adenosine cofactors”. PLoS Biology 2016, 3, e1002396.

  • Alcolombri,U.; Laurino, P.; Lara-Astiaso, P.; Vardi, A.; Tawfik D. S. “DddD is a CoA-Transferase/Lyase Producing Dimethylsulfide in the Marine Environment” Biochemistry 2014, 34, 5473–5475. This article has been chosen to be highlighted on the journal’s home page.

  • Fumagalli, L.; Pallavicini, M.; Budresi, R.; Bolchi, C.; Canovi, M.; Chiodini, G.; Gobbi, M.; Laurino, P.; Micucci, M.; Straniero, V.; Valoti, E.; “6-Methoxy-7-benzofuranoxy and 6-Methoxy-7-indolyloxy Analogues of 2-[2-(2,6-Dimethoxyphenoxy)ethyl]aminomethyl-1,4-benzodioxane (WB4101):1 Discovery of a Potent and Selective α1D-Adrenoceptor Antagonist” J. Med. Chem. 2013, 16, 6402–6412.

  • Azzouz, N.; Kamena, F.; Laurino, P.; Kikkeri, R.; Mercier, C.; Cesbron-Delauw, M-F.; Dubremetz, J-F.; De Cola, L.; Seeberger, P. H. “Toxoplasma gondii secretory proteins bind to sulfated heparin structures.” Glycobiol., 2013, 1, 106–120.

  • Suzuki, Y; Laurino, P.; McQuade D. T.; Seeberger P. H. “A Capture and Release Catalytic Flow System”, Helv. Chim. Acta 2012, 12, 2578–2588.

  • Laurino, P.; Hernandez, H.; Bräuer, J.; Grützmacher, H.; Tauer, K.; Seeberger, P. H. “Snowballing Radical Generation Leads to Ultrahigh Molecular Weight Polymers” Macromol. Rapid Commun. 2012, 20, 1770–1774.

  • Laurino, P.; Kikkeri, R.; Seeberger, P. H. “Continuous-flow reactor–based synthesis of carbohydrate and dihydrolipoic acid–capped quantum dots” Nat. Prot. 2011, 6, 1209–1220.

  • Laurino, P.; Kikkeri, R.; Azzouz, N.; Seeberger, P. H. “Detection of Bacteria Using Glyco-Dendronized Polylysine Prepared by Continuous Flow Photofunctionalization” Nano Lett., 2011, 11, 73–78.

  • Kikkeri R.; Hong, S. Y.; Grünstein, D.; Laurino, P.; Seeberger, P. H. “Carbohydrate-based Nanoscience: Metallo-glycodendrimers and Quantum Dots as Multivalent Probes“ Beilstein Bozen Symposium "Functional Nanoscience" May 17th–21st, 2010.

  • Christina, D.; Laurino, P.; Azzouz, N.; Seeberger, P. H. “Accelerated Continuous Flow RAFT polymerization” Macromol. 2010, 43, 10311–10314.

  • Bernardes, G. J. L.; Kikkeri, R.; Maglinao, M.; Laurino, P.; Collot, M.; Hong, S. Y.; Lepenies, B.; Seeberger, P. H. “Design, synthesis and biological evaluation of carbohydrate functionalized cyclodextrins and liposomes for hepatocyte-specific targeting” Org. Biomol. Chem. 2010, 21, 4987–4996.

  • Kikkeri, R.; Laurino, P., Odedra, A.; Seeberger, P. H. “Synthesis of carbohydrate-functionalized quantum dots in microreactors”. Angew. Chem. Int. Ed. Engl. 2010, 49, 2054–2057.

  • Laurino, P.; Odedra, A.; Mak, X. Y.; Gustafsson, T.; Geyer, K.; Seeberger, P. H. “Microfluidic devices for organic processes”. Chemical Reactions and Processes under Flow condition (RSC publishing 2010).

  • Mak, X. Y.; Laurino, P.; Seeberger, P. H. “Asymmetric reactions in continuous flow”. Beilstein J. Org. Chem. 2009, 5, 1–11.

  • Mak, X. Y.; Laurino, P.; Seeberger, P. H. “Synthesis of pharmaceutical and bio-active compounds in microreactors” Chemistry Today 2009, 27, 15–18.

  • Kikkeri, R.; Lepenies, B.; Adibekian, A.; Laurino, P.; Seeberger P. H. “In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots”. J. Am. Chem. Soc. 2009, 131, 2110–2112.