Bogna M. Ignatowska-Jankowska

Bogna Ignatowska-Jankowska
Postdoctoral Scholar
Ph.D. University of Gdansk (Poland) 2011
M.S. University of Gdansk (Poland), 2006

I am a neurobiologist with over 15 years of experience in experimental research in animal models of behavior.  I specialize in the physiology of the central nervous system, in particular, the function of the endocannabinoid system in the brain, neuropsychopharmacology, and function of the brain reward system.


Professional Experience

  • The Hebrew University of Jerusalem, Edmond and Lily Safra Center for Brain Sciences (Israel), Postdoctoral Fellow, 2014-2017
  • Virginia Commonwealth University, Department of Pharmacology and Toxicology (USA), Postdoctoral Associate, 2011-2014
  • University of Gdansk, Department of Animal Physiology (Poland), Graduate Research Assistant, Teaching Assistant, Project Manager, Principal Investigator, 2006-2011



  • Japan Society for Promotion of Science (JSPS)  International Fellowship for Overseas Researchers in Japan (2017-2019)
  • Postdoctoral Scientific Achievement Award for the Presentation at the 28th Annual International Cannabinoid Research Society Symposium on Cannabinoids, 1-5 July 2018, Leiden, Netherlands
  • The Shimon Peres Fellow Award for Outstanding Academic Achievement during Postdoctoral studies, at the in Edmond and Lily Safra Center for Brain Sciences at The Hebrew University of Jerusalem, Israel (2016-2017)
  • Lady Davis Postdoctoral Fellowship, Hebrew University of Jerusalem, Israel (2016-2017)
  • Postdoctoral Scholar Award from the Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA (2013)
  • Foundation for Polish Science Research Grant within Ventures Program co-financed by the EU European Regional Development Fund (2010-2011)
  • Polish Ministry of Science and Higher Education Research Grant for PhD students (2009-2011)
  • Research Grant for PhD students from European Social Fund in the framework of the Program of implementing the elements of modern education forms at the University of Gdansk (2009-2010)
  • Support from the European Union within the European Social Fund in the framework of the project "InnoDoktorant - Scholarships for PhD students, I edition (2008-2009)


Select Publications

  • Hermes DJ, Jacobs IR, Key MC, League AF, Yadav-Samudrala BJ, Xu C, McLane VD, Nass SR, Jiang W, Meeker RB, Ignatowska-Jankowska BM, Lichtman AH, Li Z, Wu Z, Yuan H, Knapp PE, Hauser KF, and Fitting S. (2020) Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure leads to an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids. J Neuroinflamm 17, 345.
  • Mustafa M, Donvito G, Moncayo L, Mustafa M, Donvito G, Moncayo L, Swafford A, Poklis J, Grauer R, Olszewska T, Ignatowska-Jankowska B, Kendall D, Lu D, Lichtman AH. (2020) In vivo evaluation of the CB1 allosteric modulator LDK1258 reveals CB1-receptor independent behavioral effects. Pharmacol Biochem Behav, 190: 172840. doi:10.1016/j.pbb.2019.172840
  • Jacobs IR, Xu C, Hermes DJ, Xu C, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM and Fitting S. (2019) Inhibitory control deficits associated with upregulation of CB1R in the HIV-Tat transgenic mouse model of HAND. J Neuroimmune Pharmacol, 14(4):661–678. doi:10.1007/s11481-019-09867-w
  • Mukherjee DM#, Ignatowska-Jankowska BM#, Itskovits E#, Gonzales BJ, Turm H, Izakson L, Haritan D, Bleistein N, Cohen C, Amit I, Shay T, Grueter B, Zaslaver A and Citri A. (2018) Salient experiences are represented by unique transcriptional signatures in the mouse brain. #authors contributed equally. eLife  doi: 10.7554/eLife.31220
  • Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R. (2019) N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology, 19; 148: 320-331.
  • Xu C, Hermes DJ , Nwanguma B, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska BM, and Fitting S. (2017) Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. Molecular and Cellular Neuroscience 83: 92-102.
  • Owens RA, Mustafa MA, Ignatowska-Jankowska BM, Damaj MI, Beardsley PM, Wiley JL, Niphakis MJ, Cravatt BF, Lichtman AH. (2017) Inhibition of the Endocannabinoid-Regulating Enzyme Monoacylglycerol Lipase Elicits a CB1 Receptor-Mediated Discriminative Stimulus in Mice, Neuropharmacology 125: 80-86.
  • Owens RA, Ignatowska-Jankowska B, Mustafa M, Beardsley PM, Wiley JL, Niphakis MJ, Cravatt BF, Lichtman AH. (2016) Endogenous Cannabinoids Elicit a Discriminative Stimulus. Journal of Pharmacology and Experimental Therapeutics, 358(2):306-314.
  • Neuner S, Wilmott LA, Garfinkel BP, Ignatowska-Jankowska BM,  Citri A, Orly J, Lu L, Overall RW, Mulligan MK, Kempermann G, Williams RW, O’Connell KMS, Kaczorowski CC.(2016) Systems genetics identifies Hp1bp3 as a novel regulator of cognitive aging. Neurobiology of Aging, 46:58-67.
  • Grim T, Samano KL, Ignatowska-Jankowska BM, Tao Q, Sim-Selley L, Selley D, Wise L, Poklis A, Lichtman AH. (2016) Pharmacological characterization of the first generation abused synthetic cannabinoid CP47,497. Journal of Basic and clinical Physiology and Pharmacology 27(3):217-28
  • Xu C, Hermes DJ, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, and Fitting S. (2016) Cannabinoids occlude the HIV-1 Tat-induced decrease in GABAergic neurotransmission in prefrontal cortex slices. Journal of Neuroimmune Pharmacology 11(2):316-31
  • Mukhopadhyay P, Baggelaar M, Erdelyi K, Cao Z, Cinar R, Fezza F, Ignatowska-Jankowska B, Wilkerson J, van Gils N, Hansen T, Ruben M, Soethoudt M, Heitman L, Kunos G, Maccarrone M, Lichtman A, Pacher P, van der Stelt M. (2016) The novel, orally available and peripherally restricted selective cannabinoid CB2-receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity. British Journal of Pharmacology 173(3):446-58.
  • Ignatowska-Jankowska B, Baillie GL, Kinsey S, Crowe M, Ghosh S, Owens RA, Damaj MI, Poklis J, Wiley JL, Pertwee RG, Zanda M, Zanato C, Greig IR, Lichtman AH, Ross RA. (2015) A CB1 Receptor Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with no Psychoactive Effects. Neuropsychopharmacology 40(13):2948-2959.
  • Ignatowska-Jankowska B, Wilkerson J, Mustafa M, Abdullah R, Niphakis M, Wiley JL, Cravatt BF, Lichtman AH (2015) Selective monoacylglycerol lipase inhibitors: Antinociceptive vs. cannabimimetic effects in mice. Journal of Pharmacology and Experimental Therapeutics 353(2):424-432.
  • Polkis J, Clay DJ, Ross RA, Greig IR, Ignatowska-Jankowska BM, Abdullah RA, Lichtman AH, Poklis A.  (2015) HPLC/MS/MS Determination of ZCZ-011, a Novel Pharmacological Tool for Investigation the Cannabinoid Receptor in Mouse Brain Using Clean Screen FAStTM Column Extraction. Journal of  Analitical Toxicology, 39(5):353-358
  • Gamage TF, Ignatowska-Jankowska B, Muldoon PP, Cravatt BF, Damaj MI, Lichtman AH. (2015) Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice. Drug and Alcohol Dependence 146:7-16.
  • Ignatowska-Jankowska B, Ghosh S, Crowe M, Kinsey S, Niphakis MJ, Abdullah RA, Tao Q, O’Neal S, Walentiny  DM, Wiley JL, Cravatt BF, Lichtman AH. (2014) In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: Antinociceptive activity without cannabimimetic side effects. British Journal of Pharmacology 171(6):1392-1407
  • Schlosburg JE, Kinsey SG, Ignatowska-Jankowska B, Ramesh D, Abdullah RA, Tao Q, Booker L, Long JZ, Selley DE, Cravatt BF, Lichtman AH. (2014) Prolonged monoacylglycerol lipase blockade causes equivalent CB1-receptor mediated adaptations in FAAH wild type and knockout mice. J Pharmacology and Experimental Therapeutics 350 (2), 196-204.
  • Gamage T, Ignatowska-Jankowska B, Abdelrahman M, Trembleau L, Thakur G, Tichkule R, Poklis J, Ross RA, Pertwee RG, Lichtman AH. (2014) Investigation of the in vivo pharmacological effects of the CB1 receptor allosteric modulator Org-27569. Journal of Behavioural Pharmacology, 25(2):182-185.
  • Ignatowska-Jankowska B, Muldoon PP, Lichtman AH, Damaj MI. (2013) The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice. Psychopharmacology (Berl), 229 (4), 591-601.
  • Fitting S, Ignatowska-Jankowska B, Bull C, Skoff RP, Lichtman AH, Wise LE, Fox MA, Su J, Medina AE, Krahe TE, Knapp PE, Guido W, Hauser KF (2013) Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in HIV-1 Tat transgenic mice. Biological Psychiatry, 73 (5), 443-453.
  • Ignatowska-Jankowska B, Jankowski MM, Swiergiel AH. (2011) Cannabidiol decreases body weight gain in rats: involvement of CB2 receptors, Neuroscience Letters, 490, 82-84.
  • Jankowski MM, Ignatowska-Jankowska B, Glac W., Swiergiel AH. (2010) Cocaine administration increases CD4/CD8 lymphocytes ratio in peripheral blood despite lymphopenia and elevated corticosterone. International Immunopharmacology, 10, 1229-1234.
  • Ignatowska-Jankowska B, Jankowski M, Glac W, Swiergiel AH. (2009) Cannabidiol-induced lymphopenia does not involve NKT and NK cells. Journal of Physiology and Pharmacology, Suppl 3, 60, 99‑103.
  • Trojniar W, Plucinska K, Ignatowska-Jankowska B, Jankowski M. (2007) Damage to the nucleus accumbens shell but not core impairs ventral tegmental area stimulation-induced feeding, Journal of Physiology and Pharmacology, (Suppl. 3), 58, 63-71.