Publications & Presentations

2021

*Journals

  1. League AF, Gorman BL, Hermes DJ, Johnson CT, Jacobs IR, Yadav-Samudrala BJ, Poklis JL, Niphakis MJ, Cravatt BF, Lichtman AH, Ignatowska-Jankowska BM, and Sylvia Fitting S. (2021) Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat. Frontiers in Neurology doi.org/10.3389/fneur.2021.651272
     
  2. Hermes DJ, Yadav-Samudrala BJ, Xu C, Paniccia JC, Meeker RB, Armstrong ML, Reisdorph N, Cravatt BF, Mackie K, Lichtman AH,  Ignatowska-Jankowska BM, Lysle DT, Fitting S. (2021)  GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration. Experimental Neurology  341:113699. 341:113699.  doi: 10.1016/j.expneurol.2021.113699

*Oral and Poster Presentations​

  1. OIST Internal Seminar:
    Dr. Da Guo "Dig deep to feel the rhythms at bottom of brain: recording the inferior olive activity in alive mice"
    - Date: Friday, November 12, 2021
    - Place: L4E01,OIST and Zoom

  2. Poster presentation at the annual meeting of the SfN: Vrieler N, Lefler Y, Amsalem O, Medvedev N, Vaso K, Gurkan-Ozer A., Segev I, Uusisaari MY and Yarom Y. Fast depolarizing events triggered by synaptic inputs suggest activation of intrinsic regenerative currents in axonal spines. (Trainee Professional Development Award). 8-11Nov 2021

  3. Oral presentation at 31st International Cannabinoid Research Society (ICRS) Symposium on Cannabinoids: Ignatowska-Jankowska B, Gurkan-Ozer A., Kuck A, Niphakis M, Ogasawara D, Cravatt BF, Uusisaari MY. Distinct kinematic characteristics of MAGL and FAAH inhibition in high precision 3D motion capture analysis of freely behaving mice. Jerusalem, Israel, 21-24 June 2021.
     
  4. Presentation at the Society for Neuroscience (SfN) Global Connectome Virtual Event. Ignatowska-Jankowska B, Gurkan-Ozer A., Kuck A, Niphakis M,  Ogasawara D, Cravatt BF,Uusisaari MY.  Rodent 3D Motion Capture system uncovers distinct behavioral effects of cannabinoids in freely moving mice. SfN, January 11-13th 2021
     
  5. Poster Presentation at the Society for Neuroscience (SfN) Global Connectome Virtual Event. K.Dorgans, B.Kuhn, Uusisaari MY. Imaging subthreshold voltage oscillation with cellular resolution in the inferior olive in vitro. SfN, January 12th 2021

2020

*Journals

  1. Neil Dalphin, Kevin Dorgans, Eugene Khaskin, Bernd Kuhn. Voltage imaging of cortical oscillations in layer1 with two-photon microscopy.     https://doi.org/10.1523/ENEURO.0274-19.2020
     
  2. Hermes DJ, Jacobs IR, Key MC, League AF, Yadav-Samudrala BJ, Xu C, McLane VD, Nass SR, Jiang W, Meeker RB, Ignatowska-Jankowska BM, Lichtman AH, Li Z, Wu Z, Yuan H, Knapp PE, Hauser KF, and Fitting S. (2020) Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure leads to an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids. Journal of Neuroinflammation 17, 345. https://doi.org/10.1186/s12974-020-01971-6 
     
  3. Dorgans K, Kuhn B, Uusisaari MY(2020) Imaging subthreshold voltage oscillation with cellular resolution in the inferior olive in vitro. Frontiers  doi: 10.3389/fncel.2020.607843

*Oral and Poster Presentations​

  1. Science Digest Talk:
    Dr. Kevin Dorgans on "In vitro imaging of subthreshold voltage oscillation in the inferior olive"
    - Date: Thursday, October 22, 2020
    - Place: C209, OIST and Zoom
     
  2. Science Digest Talk:
    Dr. Ignatowska-Jankowska on "Distinct behavioral effects of cannabinoids in 3D motion capture of freely moving mice"
    - Date: Monday, June 29, 2020
    - Place: C700, OIST and Zoom
     
  3. Poster presentation at the Federation of European Neuroscience Societies (FENS) Virtual FENS Forum: Ignatowska-Jankowska B,Gurkan-Ozer A., Kuck A, Micah Niphakis, Daisuke Ogasawara, Benjamin F Cravatt,Uusisaari MY.  Distinct behavioral effects of cannabinoids in 3D motion capture of freely moving mice Virtual FENS Forum 2020,  1-15 July.
     
  4. Poster presentation at the 43rd Annual Meeting of Japan Neuroscience Society (JNS): Guo D, Dorgans K, Uusisaari MY. In vivo network activity of mouse inferior olive neurons. JNS, July 29 - August 1, 2020.
     
  5. Poster presentation at the 43rd Annual Meeting of Japan Neuroscience Society (JNS): Lacava SA, Uusisaari MY. The mouse tail response to a balance perturbation. JNS, July 29 - August 1, 2020.
     
  6. Poster Presentation Prize at "PDS research summit 2020" in Stellenbosch University, Western Cape, South Africa: Dorgans K. Imaging subthreshold voltage oscillation with cellular resolution in the inferior olive in vitro. November, 2020.

       

2019

*Journals

  1. Vrieler N., Loyola S., Yarden-Rabinowitz Y., Medvedev N., Hoogland T., De Zeeuw CI., De Schutter E., Yarom Y., Negrello M., Torben-Nielsen B., Uusisaari MY. Variability and directionality of inferior olive neuron dendrites revealed by detailed 3D characterization of an extensive morphological library. Brain Structure and Function 224: 1677-1695. doi: 10.1007/s00429-019-01859-z
     
  2. Mustafa M, Donvito G, Moncayo L, Swafford A, Poklis J, Grauer R, Olszewska T, Ignatowska-Jankowska BM, Kendall D, Lu D, Lichtman AH. (2020) In vivo evaluation of the CB1 allosteric modulator LDK1258 reveals CB1-receptor independent behavioral effects. Pharmacol Biochem Behav, 190: 172840. doi:10.1016/j.pbb.2019.1728402.  
     
  3. Jacobs IR, Xu C, Hermes DJ, Xu C, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM and Fitting S. (2019) Inhibitory control deficits associated with upregulation of CB1R in the HIV-Tat transgenic mouse model of HAND. J Neuroimmune Pharmacol, 14(4):661–678. doi:10.1007/s11481-019-09867-w3.    
     
  4. Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R. (2019) N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology, 19; 148: 320-331. doi: 10.1016/j.neuropharm.2018.03.020.
     
  5. Dorgans  K,  Demais  V,  Bailly  Y,  Poulain  B,  Isope  P,  Doussau  F,  Short-term plasticity  at  cerebellar  granule  cell  to  molecular  layer  interneuron  synapses expands  information  processing.   ELife.   2019  May  13;8.   pii:   e41586.   doi:10.7554/eLife.41586.
     
  6. Ozcan OO, Wang X, Binda F, Dorgans K, De Zeeuw C, Gao Z, Aertsen, KumarA,  Isope  P.  Differential  Coding  Strategies  in  Glutamatergic  and  GABAergic Neurons in the Medial Cerebellar Nucleus.  J Neurosci.  2020 Jan 2;40(1):159-170.  doi:10.1523/JNEUROSCI.0806-19.2019.  Epub 2019 Nov 6.
     
  7. Straub I, Witter L, Eshra A, Hoidis M, Byczkowicz N, Maas S, Delvendahl I, Dorgans K, Savier E, Bechmann I, Krueger M, Isope P, Hallermann S. Gradients in the mammalian cerebellar cortex enable Fourier-like transformation and improve storing capacity.Elife. 2020 Feb 5;9. pii: e51771. doi: 10.7554/eLife.51771
     

*Books and other one-time publications

  1. Online database of inferior olive neurons published on neuromorpho.org http://neuromorpho.org/NeuroMorpho_ArchiveLinkout.jsp?ARCHIVE=Uusisaari&DATE=2019-12-13
     

*Oral and Poster Presentations​

  1. Poster presentation at the annual meeting of the SfN: Vrieler N, Uusisaari MY and Yarom Y. On the organization of electrical coupling between inferior olive neurons, and its influence on synchronized rhythmicity. 19-23 Oct 2019
     
  2. Ignatowska-Jankowska BM, Kuck A, Uusisaari MY: Talk at CannX 4th International Medical Cannabis Conference, Tel Aviv, Israel. Kinematic signatures of cannabinoids in 3D motion capture in mice, 9-10 Sept 2019
     
  3. Ignatowska-Jankowska BM, Poster at 29th Annual International Cannabinoid Research Society Symposium on Cannabinoids. Bethesda, USA. (ICRS/NIDA Travel Award). 29 Jun-4 July19
     
  4. Guo DDorgans K, Uusisaari MY. In vivo calcium imaging of mouse inferior olive neurons. Cerebellum Conference GRC, Les Diablerets, Switzerland, July 14. - 19., 2019
     
  5. Synaptic operational rules for locomotor adaptation in the cerebellum.  Spaeth et al.  Gordon conference, les Diablerets, July2019. Best poster award
     
  6. Organization of the temporal coding rules of the sensorimotor information in the cerebellar modules. Rossi, Dorgans et al. Cerebellum Days, Strasbourg, January 2019. Best poster award
     
  7. Gradients in the mammalian cerebellar cortex enable Fourier-like transformation and improve storing capacity.  Straub I, Witter L, Eshra A, Hoidis M, Byczkow-icz  N,  Maas  S,  Delvendahl  I,  Dorgans  K,  Savier  E,  Bechmann  I,  Krueger  M,Isope P, Hallermann S. Gordon conference, les Diablerets, July2019

2018

* Journals​

  1. Hermes DJ, Xu C, Poklis JL, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. ​Journal of Neuropharmacology.  doi: 10.1016/j.neuropharm.2018.08.013. (2018)
     
  2. Kuck, A., Stegeman DF., van der Kooij H., van Asseldonk EHF. Changes in H-Reflex Recruitment After Trans-Spinal Direct Current Stimulation With Multiple Electrode Configurations. Frontiers in Neuroscience, Neural Technology DOI: https://doi.org/10.3389/fnins.2018.00151 (2018)
     
  3. Kuck A., Stegeman DF, van Asseldonk EHF. Modeling Trans-Spinal Direct Current Stimulation in the Presence of Spinal Implants”. TNSRE DOI: https://doi.org/10.1109/TNSRE.2019.2900377 (2019)
     
  4. Vrieler N., Loyola S., Yarden-Rabinowitz Y., Medvedev N., Hoogland T., De Zeeuw CI., De Schutter E., Yarom Y., Negrello M., Torben-Nielsen B., Uusisaari MY. Variability and directionality of inferior olive neuron dendrites revealed by detailed 3D characterization of an extensive morphological library. Brain Structure and Function (Available online March 30th, 2019)  DOI: https://doi.org/10.1007/s00429-019-01859-z
     

* Oral and Poster Presentations

  1. Uusisaari, MY. From dendritic and network architecture to motor organization in the olivo-cerebellar system. Invited talk at Helsinki University, May 8th, 2018
     
  2. Uusisaari, MY. Invited talk at joint OIST/KAIST symposium: Intelligence in Biological Systems and Its Application to Machines. Daejeon, Korea, June 4-5, 2018
     
  3. Ignatowska-Jankowska BM.  Emerging behavioral models: From 3D motion capture to behavioral transcriptomics. Plenary lecture at Polish Scientific Networks (PNS): Science & Medicine Conference, Lodz, Poland, June 21-23, 2018
     
  4. Ignatowska-Jankowska BM, Hermes DJ, Xu C, Jacob IR, Meeker RB, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH and Fitting S. Inhibition of FAAH protects against microglial activation and neurotoxicity induced by HIV-1 Tat protein in vitro. Oral presentation ay Annual International Cannabinoid Research Society Meeting, Leiden, Netherlands, 1-4 July 2018
     
  5. Ignatowska-Jankowska BM, Hermes DJ, Xu C, Jacobs IR, Meeker RB, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH and Fitting S. Upregulation of endocannabinoid signaling is neuroprotective against HIV-1 Tat neurotoxicity in vitro. FENS, Berlin, Germany, 7-11 July 2018
     
  6. Ignatowska-Jankowska BM, Xu C, Hermes DJ, Jacobs IR, Meeker RB, Mackie K, Niphakis MJ, Cravatt  BF, Lichtman  AH, and Fitting S. Neuroprotective effects of endocannabinoids in models of neuronal damage induced by HIV-1 Tat protein. Oral presentation at 41st  Annual Japan Neuroscience Society Meeting (JNS), Kobe, Japan. July 25 - 27, 2018
     
  7. Tang A, Uusisaari MY. Axonal Spike Bursting in the Inferior Olive is Oscillatory-State Dependent. Oral presentation at at 41st  Annual Japan Neuroscience Society Meeting (JNS), Kobe, Japan. July 25 - 27, 2018
     
  8. Kuck A,  Ignatowska-Jankowska BM, Uusisaari MYApplication of real-time marker-based motion capture for the kinematic analysis of freely behaving mice. SfN Annual Meeting, San Diego, USA, November 3. - 7., 2018
     
  9. Ignatowska-Jankowska BM. New pharmacological strategies to target the endocannabinoid system. Department of Biopharmacy, Medical University in Lublin, Poland. December 18th, 2018 
     
  10. Ignatowska-Jankowska BM. Emerging behavioral models: from 3D motion capture to behavioral transcriptomics. Lecture for Pharmacy PhD Program at the Medical University in Lublin, Poland. December 19th, 2018
     
  11. Kuck A,  Ignatowska-Jankowska BM, Uusisaari MYApplication of passive marker-based motion capture for the kinematic analysis of freely behaving mice. OIST/Osaka University joint symposium, Osaka, Japan, January 28. - 29., 2019
     
  12. Lacava S, Uusisaari MYA motion capture study of Acoustic Startle Response in mice under different lighting conditions. OIST/Osaka University joint symposium, Osaka, Japan, January 28. - 29., 2019
     
  13. Uusisaari MY. Seeking modularity in motor timing. Invited talk at OIST/Osaka University joint symposium, Osaka, Japan, January 28. - 29., 2019

2017

  1. Uusisaari, MYFrom Morphology to network activity: dendritic clustering and oscillatory behavior in inferior olive neurons. Japanese Neuroscience Society meeting 2017, Chiba, Japan, July 20-23 (2017).
     
  2. Uusisaari, MY.  Dendritic architecture and dynamic activity clustering in the inferior olive. Gordon Research Conference on Cerebellum, Lewinston, USA, July 30 - August 4 (2017).
     
  3. Tang, A., Uusisaari, MYAxonal spike bursting in inferior olive cells is oscillation state-dependent. Australian Neuroscience Society meeting, Sydney, Australia, December 3 - 6 (2017).