Kohgaku Eguchi
![DESCRIBE PHOTO](https://groups.oist.jp/sites/default/files/imce/u111989/eguchi-san.jpg)
Ph.D. in Information Technology, Kyushu Institute of Technology, Fukuoka, Japan
MSc in Information Technology, Kyushu Institute of Technology, Fukuoka, Japan
BSc in Information Technology, Kyushu Institute of Technology, Fukuoka, Japan
I am interested in the molecular mechanisms of synaptic function using electrophysiological and immunoelectron microscopic techniques, particularly focusing on the physiological role of phospholipid-protein interactions at synapses.
Professional Experience
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Institute of Science and Technology Austria (Klosterneuburg, Austria), Postdoctoral fellow (PI: Ryuichi Shigemoto), 2017 - 2023
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Okinawa Institute of Science and Technology Graduate University (Okinawa, Japan), Staff scientist (PI: Tomoyuki Takahashi), 2014 - 2017
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Okinawa Institute of Science and Technology Graduate University (Okinawa, Japan), Postdoctoral Scholar (PI: Tomoyuki Takahashi), 2007 - 2014
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Kyushu Institute of Technology (Fukuoka, Japan), Graduate researcher (PI: Kiyonori Yoshii), 2002 - 2007
Grants & Awards
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Cellular Neurophysiology Editors’ Pick 2021, Frontiers in Cellular Neuroscience, 2021
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Marie Skłodowska-Curie Individual Fellowship, European Commission, 2018 - 2020
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Grant-in-Aid for Young Scientists (B), JSPS, Japan, 2015 - 2017
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Grant-in-Aid for Young Scientists (B), JSPS, Japan, 2012 - 2014
Technical Skills
Patch-clamp recording (in vitro, brain slices), Transmission electron microscopy, SDS-digested freeze-fracture replica labeling (SDS-FRL), Ultra-thin section TEM, In Utero/vivo electroporation, Mouse peeled lingual epithelium preparation, programming (R, Python, C), conventional statistics, statistical modeling
Significant Publications
1. Eguchi K.*, Le Monnier E., & Shigemoto R*. (2023). Nanoscale phosphoinositide distribution on cell membranes of mouse cerebellar neurons. The Journal of Neuroscience, in Press. *Corresponding authors
2. Eguchi K.*, Velicky P., Hollergschwandtner E., Itakura M., Fukuzawa Y., Danzl JG. & Shigemoto R*. (2020). Advantages of Acute Brain Slices Prepared at Physiological Temperature in the Characterization of Synaptic Functions. Frontiers in Cellular Neuroscience, 14:63. *Corresponding authors, Cellular Neurophysiology Editors’ Pick 2021
3. Eguchi K.*, Taoufiq Z., Thorn-Seshold O., Trauner D., Hasegawa M. & Takahashi T*. (2017). Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held. The Journal of Neuroscience, 37(25):6043-6052. *Corresponding authors
4. Taoufiq Z.*, Eguchi K.*, & Takahashi T. (2013). Rho-Kinase Accelerates Synaptic Vesicle Endocytosis by Linking Cyclic GMP-Dependent Protein Kinase Activity to Phosphatidylinositol-4,5-Bisphosphate Synthesis. The Journal of Neuroscience, 33(29): 12099-12104. *Equally contributed authors
5. Eguchi K.*, Nakanishi S., Takagi H., Taoufiq Z., Takahashi T*. (2012). Maturation of a PKG-Dependent Retrograde Mechanism for Exoendocytic Coupling of Synaptic Vesicles. Neuron, 74(3): 517–529. *Corresponding authors
6. Eguchi K., Ohtubo Y., Yoshii K. (2008). Functional Expression of M3, a Muscarinic Acetylcholine Receptor Subtype, in Taste Bud Cells of Mouse Fungiform Papillae. Chemical Senses, 33(1): 47-55.