Virtual Seminar"Bio-functionalized interfaces for molecule detection at the physical limit"Gaetano Scamarcio


Monday, May 10, 2021 - 16:00




Micro/Bio/Nanofluidics (Shen) Unit would like to invite you to the virtual seminar by Prof. Gaetano Scamarcio on May 10 (Monday).
Date: Monday, May 10, 2021
Time: 16:00-17:00
**Zoom session

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Meeting ID: 927 2760 1468
Passcode: 211777


Gaetano Scamarcio
Physics department
University of Bari & CNR-Institute of Photonics and Nanotechnologies, Italy


Bio-functionalized interfaces for molecule detection at the physical limit


We have demonstrated that label-free, mass-manufacturable, bio-electronic sensors based on capacity-coupled large electrolyte-gated transistors can detect a biomarker at the physical-limit. Selective detection of relevant proteins (e.g. IgG, IgM, CRP) is strikingly demonstrated also in real fluids, such as diluted saliva or whole serum.  The sensing mechanism, triggered by the affinity binding event, is explained in terms of a work-function change that is amplified in the gating-field through collective surface interactions. The proposed immunoassay single-molecule transistor platform (SiMoT) is general and can revolutionize the current approach to bio-marker detection.


Prof. Amy Shen

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