Virtual Seminar"Miniaturized and Microfluidic Electrochemical Sensors"Jaligam Murali Mohan


Thursday, July 21, 2022 - 15:00




Micro/Bio/Nanofluidics (Shen) Unit would like to invite you to the virtual seminar by Dr. Jaligam Murali Mohan on July 21  (Thursday).
Date: July 21, 2022
Time: 03:00-03:30PM
**Zoom session

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Meeting ID: 999 0487 7372
Passcode: 936515


Dr. Jaligam Murali Mohan
Department of Mechanical Engineering
Birla Institute of Technology & Sciences, India



Miniaturized and Microfluidic Electrochemical Sensors


Modern analytical and clinical testing methods rely on laboratory-based procedures that are
expensive, time-consuming, have limited sensitivity and require significant testing
expenditures to prove their efficacy. Since point-of-care (POC) detection is crucial for more
tests to be done in the field with significant flexibility, the focus has been on developing smaller
analytical devices. Miniaturized and Microfluidic Electrochemical (MMEC) Devices, which
utilize unique and smart materials, have been in high demand in the analytical science arena
owing to their high sensitivity, mobility, ease of operation, and short analysis time. Such
devices detect trace amounts of analytes by measuring electrochemical changes, such as
voltage, current, and impedance, due to the redox reaction (oxidation or reduction) signals of
biochemical/chemical molecules using electrodes and electrochemical units. These units have
been modified for target-detection applications. They have significant benefits over traditional
testing procedures due to the sensor's capacity to detect a wide range of substances, such as
small chemical molecules and metal ions.
The research focuses on designing and developing MMEC devices with miniaturized,
inexpensive, disposable and easily affordable electrodes, which have been demonstrated for
sensing various biochemical and analytes surrounding mankind. Biochemicals such as
Ascorbic acid (AA), Dopamine (D), Uric acid (UA) and Xanthine (X), hazardous pollutants
like Hydrazine and heavy metals such as Arsenic, Copper and Mercury and picric acid have
been considered as target analytes for testing the developed miniaturized electrochemical
platforms. Herein, various fabrication approaches like CO2 Laser engraving, Ink Jet printing,
Screen printing, Pholothiography etc., were used to fabricate the MMEC devices with
miniaturized electrodes. The electrodes deployed in these devices have been fabricated from
commercially available inexpensive substrates like toray carbon fiber, graphite sheet, thread
and ITO glass sheets. Further, several surface modification approaches like drop casting and
electrodeposition were used to enhance the performance of these electrodes. These surfacemodified electrodes were integrated to develop miniaturized disposable, portable point-of-care
devices. The miniaturized electrochemical sensors presented in this work can be easily
integrated with IoT and have the potential to be employed as a point of care devices even in
remote and resource-limited settings.


Prof. Amy Shen

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