BSc, MSc, PhD (University of Tokyo)
1988 BSc, Department of Physics, Faculty of Science, University of Tokyo,
1990 MSc, Department of Physics, Faculty of Science, University of Tokyo
1994 PhD, Department of Physics, Faculty of Science, University of Tokyo
Research and Professional Experience
1992 Research Associate, Laboratory of Genetics, University of Tokyo
1995 Research fellow (HFSP long-term fellowship), King’s College London
1998 Research fellow, RIKEN Brain Science Institute
2000 PRESTO researcher, JST
2001 Unit Leader, Masai Initiative Research Unit, RIKEN
2006 Principal Investigator, OIST
2011 Associate Professor, OIST Graduate University
2019 Professor, OIST Graduate University
Iribarne, M. Nishiwaki, Y., Nakamura, S., Araragi, M., Oguri, E. and Masai, I. (2017) Aipl1 is required for cone photoreceptor function and survival through the stability of Pde6c and Gc3 in zebrafish. Sci. Rep. 7:45962.
Mochizuki, T., Luo, Y. J. Tsai, H. F. Hagiwara, A., and Masai, I. (2017) Cell division and cadherin-mediated adhesion regulates lens epithelial cell movement in zebrafish. Development 144, 708 – 719.
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T., and Masai, I. (2013). The BH3-only SNARE BNip1 mediates photoreceptor apoptosis in response to vesicular fusion defects. Dev. Cell 25, 374 – 387.
Imai, F., Yoshizama, A., Fujimori-Tonou, N., Masai, I. (2010) The ubiquitin proteasome system is required for cell-cycle progression of the lens epithelium and differentiation of lens fiber cells in zebrafish. Development 137, 3257-3268.
Yamaguchi M, Fujimori-Tonou N, Yoshimura Y, Kishi T, Okamoto H, Masai I. (2008) Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53. Development 135, 1247-1257.
Yamaguchi M, Tonou-Fujimori N, Komori A, Maeda R, Nojima Y, Li H, Okamoto H, Masai I. (2005). Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development 132, 3027-3043.
Masai I, Yamaguchi M, Tonou-Fujimori N, Komori A, Okamoto H. (2005) The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation. Development 132, 1539-1553.
Masai I, Lele Z, Yamaguchi M, Komori A, Nakata A, Nishiwaki Y, Wada H, Tanaka H, Nojima Y, Hammerschmidt M, Wilson SW, Okamoto H. (2003) N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development 130, 2479-2494.
Masai I, Stemple DL, Okamoto H, Wilson SW. (2000) Midline signals regulate retinal neurogenesis in zebrafish. Neuron 27, 251-263.
Masai I, Heisenberg CP, Barth KA, Macdonald R, Adamek S, Wilson SW. (1997) floating head and masterblind regulate neuronal patterning in the roof of the forebrain. Neuron 18, 43-57.
Masai I, Okazaki A, Hosoya T, Hotta Y. (1993) Drosophila retinal degeneration A gene encodes an eye-specific diacylglycerol kinase with cysteine-rich zinc-finger motifs and ankyrin repeats. Proc. Natl. Acad. Sci. USA. 90, 11157-11161.
Masai I, Hosoya T, Kojima S, Hotta Y. (1992) Molecular cloning of a Drosophila diacylglycerol kinase gene that is expressed in the nervous system and muscle. Proc. Natl. Acad. Sci. USA. 89, 6030-6034.