Biotechnology

Nanophotonic materials and novel sensors

Metal nanostructures are a highly attractive class of materials with unique electrochemical and optical sensing properties. Recent developments have greatly improved the sensitivity of optical sensors based on metal nanostructured arrays. We use these nanophotonic materials to develop the localized surface plasmon resonance (LSPR) sensors, for detecting molecular binding events. Our ongoing research involves areas presenting most significant challenges: integration of LSPR with complementary electrochemical techniques, long term live-cell biosensing and practical development of sensors and instrumentation for routine use and high-throughput detection.  

  1. Integrated electrochemical and nanoplamonic sensors
  2. More
  3. Nikhil's

 

Bioassays

Immunoassay diagnostic devices have benefited from the development of microfluidic techniques by reducing the required sample volume and costs per test. Nanofluidic technologies promise to reduce required sample volume even further, and introduce new physical phenomena that can improve the performance of diagnostic devices. Our ongoing research focuses on: surface chemistry and nanomaterial synthesis related to sensing, exploiting micro/nanofluidics to enhance capture efficiency.

  1. Microcontact printing
  2. Convection limited nanofluidics

 

 

Bio-MEMs  

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  1. Uniform electric field generation in circular multi-well cell culture plate/dish using polymeric inserts
  2. Microfluidic platform for tumor spheroids
  3. Tumor-on-Chip