Virtual Seminar"Longitudinal to transverse metachronal wave transitions in an in-vitro model of ciliated bronchial epithelium"Olivier Mesdjian

Micro/Bio/Nanofluidics (Shen) Unit would like to invite you to the virtual seminar by Dr. Olivier Mesdjian on October 25 (Monday).
 
----------------------------------------------------------------------
Date: Monday, October 25, 2021
Time: 16:00-17:00
**Zoom session
----------------------------------------------------------------------

Join Zoom Meeting
https://oist.zoom.us/j/94485531069?pwd=eVg3NS9aVk5YQkphS1FVMmFJQWhJQT09

Meeting ID: 944 8553 1069
Passcode: 739032

Speaker:

Dr. Olivier Mesdjian
Biophysics/Bio-engineering department
CINAM, Marseille, France

Title:

Longitudinal to transverse metachronal wave transitions in an in-vitro model of ciliated bronchial epithelium

Abstract:

Myriads of cilia beat on ciliated epithelia, which are ubiquitous in life. When ciliary beats are synchronized, metachronal waves emerge, whose direction of propagation depends on the living system in an unexplained way. We show on a reconstructed human bronchial epithelium in-vitro that the direction of propagation is determined by the ability of mucus to be transported at the epithelial surface. Numerical simulations show that longitudinal waves maximise the transport of mucus while transverse waves, observed when the mucus is rigid and still, minimize the energy dissipated by the cilia.

Host:

Prof. Amy Shen