Publications

2024
Ran-GTP assembles a specialized spindle structure for accurate chromosome segregation in medaka early embryos
Kiyomitsu A, Nishimura T, Hwang SJ, Ansai S, Kanemaki MT, Tanaka M, Kiyomitsu T.
Nature Communications 2024 Feb 1;15(1):981. doi: 10.1038/s41467-024-45251-w

2023
Ran-GTP assembles a specialized spindle structure for accurate chromosome segregation in medaka early embryos
Kiyomitsu A, Nishimura T, Hwang SJ, Ansai S, Kanemaki MT, Tanaka M, Kiyomitsu T.
bioRxiv: https://biorxiv.org/cgi/content/short/2023.07.20.549960v1

NuMA deficiency causes micronuclei via checkpoint-insensitive k-fiber minus-end detachment from mitotic spindle poles
Van Toorn, M. Gooch, A. Boerner. S, Kiyomitsu T.
Current Biology 2023 Jan.4:S0960-9822(22)1917-0. doi: 10.1016/j.cub.2022.12.017. Online ahead of print.
PMID: 36626904 https://www.cell.com/current-biology/fulltext/S0960-9822(22)01917-0?rss=yes

Using Optogenetics to Spatially Control Cortical Dynein Activity in Mitotic Human Cells
Kiyomitsu T.
Methods in Molecular Biology. 2023;2623:73-85. doi: 10.1007/978-1-0716-2958-1_5.
PMID:36602680https://link.springer.com/protocol/10.1007/978-1-0716-2958-1_5

2022
NuMA deficiency causes micronuclei via checkpoint-insensitive k-fiber minus-end detachment from mitotic spindle poles
Van Toorn, M. Gooch, A. Boerner. S, Kiyomitsu T.
bioRxiv, 2022  https://biorxiv.org/cgi/content/short/2022.10.04.510904v1

2021
Ran-GTP is non-essential to activate NuMA for spindle pole focusing, but dynamically polarizes HURP near chromosomes. in Current Biology
Tsuchiya, K. Hayashi, H. Nishina, M. Okumura, M. Sato, Y. Kanemaki, M.T. Goshima, G. Kiyomitsu  T.
Current Biology 2021 Jan 11;31(1):115-127.e3  https://www.cell.com/current-biology/fulltext/S0960-9822(20)31504-9

The Nuclear Mitotic Apparatus (NuMA) Protein: A Key Player for Nuclear Formation, Spindle Assembly, and Spindle Positioning.
Kiyomitsu T, and Boerner, S.
Frontiers in Cell and Developmental Biology. 2021 Apr 1;9:653801.https://www.frontiersin.org/articles/10.3389/fcell.2021.653801/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE