Speaker: Professor Luiza Angheluta-Bauer, Condensed Matter Physics, University of Oslo

Hosted by Professor Mahesh Bandi Nonlinear and Non-equilibrium Physics Unit

Abstract:

Collective structural arrangements and cell migration are important physical processes underlying tissue development and regeneration. Understanding the complexity of cell-cell interactions and the emergence of collective behaviors at the tissue scale presents formidable challenges both experimentally and theoretically.

In this talk, I will discuss recent theoretical work on the dynamical patterns that emerge at the tissue scale from localized rearrangements and topological defects. Using a multi-phase field model, we demonstrate that tissue fluidity stems from cell neighbor exchanges, serving as transient sources of vortical flow. This flow emerges from the relative dispersion of cells at a rate proportional to the frequency of rearrangements. Balancing collective migration with relative cell motion appears to be essential for maintaining tissue shape and fluidity. Using a cell-based model, we study the tissue's response to the presence of a vortex. While solid-like behavior tends toward conical shapes, localized fluidization triggers the transition to a tube, which is fundamental in biological tissues.

Prof. Dr. Myung Hee Kim

Korea Research Institute of Bioscience and Biotechnology

COI Team Announces Call for New Projects! Seeking initiatives aligned with our core themes—Healthy Mind, Healthy Body, and Healthy Environment. Encouraging proposals with tangible outcomes for a real impact.

Nov 21 - Dec 01 Laurin Ostermann (Senior Scientist, University of Innsbruck, Austria)

Nov 21 - Dec 08 Karol Gietka (Postdoc, University of Innsbruck, Austria)

Nov 20 - Nov 24 Lewis Ruks (Postdoc, NTT Basic Research Labs)

Visit of Prof. Gediminas Juzeliūnas, Professor, Vilnius University, Lithuania

Visit of Dr. Antonín Doupal and Dr. Marijn Boone from TESCAN, Brno, Czech Republik.

They will introduce their new equipment
the TEM for analytical 4D STEM
and MicroCT

Following the success of the previous ORC survey, and the Student Council surveys it was modeled on, the ORC Council is running the biannual survey (~5-10min) to gauge research employee satisfaction at OIST. Please fill the survey in this link: https://groups.oist.jp/ganjuu/oist-researcher-community-survey-2023. 

Everyone is encouraged to contribute to the development and shaping of the community, please consider nominating yourself or a colleague for the 2024 OIST Researcher Community (ORC) Council!