Seminar by Prof. Jun YOKOTA. "Cancer Genome."

Cell Signal Unit(Yamamoto Unit) would like to invite you to a seminar by Jun YOKOTA.

Speaker: Prof. Jun YOKOTA

Senior Group Leader, Genomics and Epigenomics of Cancer Prediction Program
Institute of Predictive and Personalized Medicine of Cancer (IMPPC) Barcelona, Spain.

Title: Cancer Genome

Abstract: Cancer is a disease of the gene.  Many genes are somatically mutated in cancer cells during their development.  Distributions of genetic polymorphisms in cancer patients are different from those in non-cancer individuals.  In particular, the presence of germline mutation is responsible for the development of familial cancers.  Therefore, molecular mechanisms of cancer development and its progression can be elucidated if we could understand the genomic diversity among cancer cells as well as among cancer patients.  Recent advances in molecular technology have made it possible to analyze the sequence, copy number, and structure of the whole genome.  Based on the information obtained by genome-wide analyses of cancer cells, several molecular targets useful for therapy have been identified to date.  Comparative analysis of whole genome structure between cancer patients and non-cancer individuals has also given clues to develop a novel way of cancer prevention.  Here I summarize our knowledge on the diversity of human cancer genome.

Host: 

Tadashi Yamamoto, Cell Signal Unit