[Seminar] Updating internal models for reward-based sequential choice decisions in the rat cingulate-motor circuits

Date: Wednesday, September 28, 2022
Time: 13:00 – 14:00
Venue: Meeting Room D015, Lab 1 and zoom (pre-registrtion is not required)
Zoom URL: https://oist.zoom.us/j/97258119571?pwd=c2lYOW9zeXVsdEhtT0VNUW93N1dwdz09
                  ID:972 5811 9571   Passcord:700064
Speaker: Dr. Daigo Takeuchi
               The University of Tokyo School of Medicine, Department of Physiology

Title:Updating internal models for reward-based sequential choice decisions in the rat cingulate-motor circuits

Abstract:

How decision algorithms are implemented in the brain has been a focus of debate for decades. In this seminar I present an experimental evidence regarding how cortical circuits connecting anterior cingulate cortex (ACC) and secondary motor cortex (M2) in rats play a role in reward-based sequential decision making. The data suggests that the ACC-M2 connections are a part of brain circuits that, based on the outcome feedback information, update the internal models of how the environment works and use them for planning subsequent choice actions. I will discuss how the reinforcement learning framework may help further dissecting the decision algorithms that these prefrontal cortical circuits implement.

Reference:

Takeuchi, D., Roy, D., Muralidhar, S. et al. Cingulate-motor circuits update rule representations for sequential choice decisions. Nat Commun 13, 4545 (2022).

https://doi.org/10.1038/s41467-022-32142-1

https://picower.mit.edu/news/when-task-adds-more-steps-circuit-helps-you-notice

Host: Neural Computation Unit
Contact: ncus@oist.jp