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Participant Institutes

  • Institute of Biochemistry and Molecular Biology, National Taiwan University (IBMB, NTU)
  • Institute of Molecular Biology and Genetics, Seoul National University (IMBG, SNU)
  • Institute of Medical Science, University of Tokyo (IMSUT)
  • Institute for Virus Research, Kyoto University (IVR, Kyoto Univ.)
  • Okinawa Institute of Science and Technology Graduate University (OIST)
  • Samsung Biomedical Research Institute, Sungkyunkwan University (SBRI, SKKU)
  • Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (SIBCB, CAS)
  • Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University (SIMS, SCHU)

Venue: OIST campus, B250

November 10 (Tue)     


November 11 (Wed)    

9:00-9:10 Opening remark: Dean of Research (George Iwama)

9:10-9:20 Information by Ichiro Masai

Session “Developmental Biology, signaling and disease model” Chair: Ichiro Masai

9:20–9:45 Lecture 1 Ichiro Masai (OIST)

Cell division and cadherin-mediated cell adhesion regulate lens epithelial cell movement in zebrafish

9:45–10:10 Lecture 2 Chan-Yen Ou (IBMB, NTU)

Cyclin-dependent kinases pathways regulate synapse formation in motor neurons

10:10–10:30 Break 20 min                            

10:30–10:55 Lecture 3 Yen-Shou Lin (IBMB, NTU)

Herbal medicines for ameliorating the Aβ-induced depolarization in primary cortical neurons

10:55–11:20 Lecture 4 Hsiu-Mei Hsieh (IBMB, NTU)

Identification of nature products to ameliorate learning memory deficit in streptozotocin-induced Alzheimer mouse model

11:20–11:45 Lecture 5 Jun-ichiro Inoue (IMSUT)

Regulation of the TRAF6-NF-B and the Calcineurin-NFATc1 pathways in RANK signal-induced osteoclastogenesis

12:00–13:30 Lunch

12:00­­–13:00 DIRECTOR MEETING (C016, Lab1)

Session “Gene regulation and genetics, ecology” Chair: Hidetoshi Saze

13:30–13:55 Lecture 6 Jeong Hoon Kim (SBRI, SKKU)

DBC1, a master regulator of β-catenin-PROX1 signaling axis

13:55–14:20 Lecture 7 Masaki Takahashi (IMSUT)

Development of an efficient Cell-SELEX using engineered isogenic cell lines to generate RNA aptamers against a cell surface protein of interest

14:20–14:45 Lecture 8 Yu-Feng Hsu (IBMB, NTU)

Diversity of phytophagous insects associated with Fagus hayatae forest

14:45–14:55 Break 10 min

Session “Structural Biology” Chair: Matthias Wolf

14:55–15:20 Lecture 9 Matthias Wolf (OIST)

Cryo-EM imaging with the Volta Phase Plate

15:20-15:45 Lecture 10 Bo OuYang (SIBCB, CAS)

NMR applications on mitochondrial carrier machinery

15:45–16:00 Break 15 min

Young investigator talk: Chair: Matthias Wolf, Ichiro Masai

“Developmental Biology and signaling”

16:00–16:10 short talk 1 (P-1) Kumiko Kobayashi (IVR, Kyoto Univ.)

Single-cell analysis of mouse segmentation clock

16:10–16:20 short talk 2 (P-2) Yi-Jyun Luo (OIST)

The Lingula genome and the patterning of BMP-chordin axis in brachiopods

16:20–16:30 short talk 3 (P-3) Shin Jeon (IMBG, SNU)

Anteroposterior limb skeletal patterning requires the bifurcating function of SWI/SNF chromatin remodeling complex in Hedgehog pathway

16:30–16:40 short talk 4 (P-4) Young-Eun Leem (SBRI, SKKU)

PRMT7 deficiency enhances adipogenesis leading to obesity-related phenotypes in mice

16:40–16:50 short talk 5 (P-5) Sang A Lee (SIMS, SCHU)

miR-31/SDHA axis regulates reprograming efficiency through mitochondrial metabolism

16:50–17:05 Break 15min

17:05–17:15 short talk-6 (P-6) Se-Hyuk Kim (SBRI, SKKU)

SSU72 functions as a gatekeeper monitoring for chromosome integrity

17:15–17:25 short talk 7 (P-7) Chia-Wei Lin (IBMB, NTU)

Investigation of the molecular pathogenesis for SCA17 through transgenic mouse model

17:25–17:35 short talk-8 (P-8) Sungho Hong (OIST)

GABA-mediated phase repulsive coupling and seasonal time coding in the suprachiasmatic nucleus

“Structural biology”

17:35–17:45 short-talk 9 (P-9) Yukihiko Sugita (OIST)

Cryo-electron microscopic analysis of influenza virus ribonucleoprotein complex during transcription

17:45–17:55 short talk 10 (P-10) Hong-Wen Chen (SIBCB, CAS)

Structural Basis of Telomerase Recruitment in Yeast

17:55-18:10 Break 15min

“Gene regulation and genetics, ecology”

18:10–18:20 short talk 11 (P-11) Eun Ji Yu (SBRI, SKKU)

Positive regulation of β-catenin-PROX1 signaling axis by DBC1 in colon cancer progression

18:20–18:30 short talk 12 (P-12) Imchang Lee (IMBG, SNU)

OrthoANI: An improved algorithm and software for genome-based species definition of Bacteria and Archaea

18:30–18:40 short talk 13 (P13) Jia-Yuan Liang (IBMB, NTU)

Systematics and Biology of Clearwing Moths - The Synanthedonini Tribe in Taiwan

“Cancer biology”

18:40–18:50 short talk 14 (P-14) Yukino Machida (IMSUT)

Maintenance of stemness of breast cancer by FRS2beta, a feedback inhibitor for HER, during tumorigenesis

18:50–19:00 short talk 15 (P-15) Zhixin Qiu (SIBCB, CAS)

Modeling liver cancer using cancer cell lines to guide the precision medicine for liver cancer

19:00–19:10 short talk 16 (P-16) Shuto Hayashi (IMSUT)

A Bayesian Method for HLA genotyping from Whole Genome Sequencing Data

19:30–21:30 Dinner + Poster session (Cafeteria level B)

November 12 (Thu)    

Session “Cell Biology” Chair: Tadashi Yamamoto

9:00–9:25 Lecture 11 Jae Bum Kim (IMBG, SNU)

Fat Tissue Dysregulation and Insulin Resistance in Obesity

9:25–9:50 Lecture 12 Jaeseok Han (SIMS, SCHU)

Disturbance of ER homeostasis and oxidative stress synergizes to cause cell death

9:50–10:15 Lecture 13 Tadashi Yamamoto (OIST)

mRNA decay machinery and its physiological roles

10:15–10:35 Break 20 min

10:35–11:00 Lecture 14 Yuri Shibata (IMSUT)

The role of polyubiquitin chains in HTLV-1 Tax-induced IKK activation

11:00–11:25 Lecture 15 Yong Tae Kwon (IMBG, SNU)

Modulation of autophagy by the N-end rule proteolytic system: its role in protein quality control and innate immunity

11:25–11:50 Lecture 16 Gang Wang (SIBCB, CAS)

The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination

12:00–13:30 Lunch    

Chair by Hidetoshi Saze

13:30–13:55 Lecture 17 Jeong Kyo Yoon (SIMS, SCHU)

Regulatory role of R-spondin-LGR4 signaling in skeletal muscle stem cell and myogenic differentiation

Session “Virology and Immunology-1” Chair: Hiroki Ishiwaka

13:55–14:20 Lecture 18 Ping Hu (SIBCB, CAS)

Acute inflammation is required for muscle regeneration

14:20–14:45 Lecture19 Kae Won Cho (SIMS, SCHU)

Adipose Tissue Immune cells: Key players in metabolicsyndromes

14:45­–15:10 Lecture 20 Tae Jin Kim (SBRI, SKKU)

Development of Putative B-1 helper T cells

15:10–15:30 Break 20 min

Young investigator talk: Chair: Hiroki Ishiwaka, Hidetoshi Saze

“Cell Biology”

15:30–15:40 short talk 17 (P-17) Koichiro Akiyama (IVR, Kyoto Univ.)

Analysis of the conserved membrane-reentrant loop of RseP, an intramembrane-cleaving protease

15:40–15:50 short talk 18 (P-18) Megumi Ikeda (IVR, Kyoto Univ.)

Dormant cells emerging from Embryonic Stem Cells sustain pluripotency in differentiation condition

15:50–16:00 short talk 19 (P-19) Shibin Hu (SIBCB, CAS)

Protein arginine methyltransferase CARM1 attenuates the paraspeckle mediated nuclear retention of mRNAs containing IRAlus

16:00–16:10 short talk 20 (P-20) Lidya Kristiani (SIMS, SCHU)

Development of High Sensitive (HS) Hi-C Method through Adaptor-Mediated Ligation and Low Density DNA Digestion

16:10–16:20 short talk 21 (P-21) Jiho Park (IMBG, SNU)

Study on the function of BubR1 in zebrafish model system

16:20-16:35 Break 15 min

16:35–16:45 short talk 22 (P-22) Moe Matsushita (IMSUT)

Identification of a novel redox-sensor that mediatesactivation of stress-responsive MAPK pathways

16:45–16:55 short talk 23 (P-23) Debojyoti De (SBRI, SKKU)

Developing an efficient and selective strategy for differentiating pluripotent stem cells

“Virology and Immunology”

16:55–17:05 short talk 24 (P-24) Taku Kureha (OIST)

CNOT3 is important for thymocyte development throughthe regulation of TCR-mediated cell death signaling

17:05–17:15 short talk 25 (P-25) Dongming Zhao (IMSUT)

Characterization of a reporter-expressing H5N1 influenza A virus in vitro and in vivo

17:15–17:25 short talk 26 (P-26) Xiangpeng Sheng (SIBCB, CAS)

An Escherichia coli O157:H7 effector inhibits host inflammation response by ubiquitylating TRAFs family

17:25-17:40 Break 15 min

 “Developmental biology and Disease model”

17:40–17:50 short talk 27 (P-27) Ji Hye Park (SBRI, SKKU)

Protein kinase B/Akt phosphorylates Histone 2A, controlling neuronal apoptosis under oxidative stress

17:50–18:00 short talk 28 (P-28) Jie Yin (SIBCB, CAS)

A secreted protein plays a key role in regulating aging related muscle atrophy

18:00–18:10 short talk 29 (P-29) Lesly Puspita (SIMS, SCHU)

In vitro disease modeling study with patient iPSc suggested metabolic impairment of Parkinson disease

18:10–18:20 short talk 30 (P-30) Mona Fendereski (SIMS, SCHU)

Directed in vitro myogenesis of human embryonic stem cells and their in vivo delivery using biomimetic materials

18:20-18:35 Break 15 min

18:35–18:45 short talk 31 (P-31) Altanbyek Volodya (SIMS, SCHU)

The imbalance of mitochondrial dynamics in ALS

18:45–18:55 short talk 32 (P-32) Su Jin Ham (IMBG, SNU)

Regulation of Parkin E3 ligase by its own UBL domain

18:55–19:05 short talk 33 (P-33) He-Pei Yu (IBMB, NTU)

Identifying a novel compound NCT016 as an anti-Alzheimer’s disease agent

19:30–21:30 Dinner + Poster session (Cafeteria level B)

November 13 (Fri)      

Session “Virology and Immunology-2” Chair: Hiroki Ishikawa

9:00–9:25 Lecture 21 Hiroki Ishikawa (OIST)

HLX1 regulates differentiation and function of CD4 T helper cells

9:25–9:50 Lecture 22 Ichiro Taniguchi (IVR, Kyoto Univ.)

HIV-1 Rev protein specifies the viralRNA export pathway by suppressing TAP/NXF1 recruitment

9:50–10:15 Lecture 23 Fajian Hou (SIBCB, CAS)

An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response

10:15–10:45 Break 30 min

10:45–11:10 Lecture 24 Satoshi Fukuyama (IMSUT)

Generation of Color-flu for in vivo imaging of influenza virus infection

11:10–11:35 Lecture 25 Jun-ichirou Yasunaga (IVR, Kyoto Univ.)

Multimodal functions of HTLV-1 bZIP factor as RNA and protein on proliferation and survival of CD4+ T cells

11:40–12:00 Group Photo

12:00– 13:30 Lunch

“Session “Cancer Biology” Chair: Sumiko Watanabe

13:30–13:55 Lecture 26 Seiya Imoto (IMSUT)

Challenges for genomic big data analysis in IMSUT

13:55–14:20 Lecture 27 Seongho Ryu (SIMS, SCHU)

The role of PRC2 in cancer stem cell maintenance

14:20-14:45 Lecture 28 Chin Ha Chung (IMBG, SNU)

UFM1 in the Control of Breast Cancer Development

14:45-15:00 Break 15 min

15:00–15:25 Lecture 29 Hyeon Ho Kim (SBRI, SKKU)

Neurofibromin 2 (NF2) controls the invasiveness of glioblastoma

15:25–15:50 Lecture 30 Susumu Goyama (IMSUT)

The role of thrombin-Par-1 pathway in myeloid leukemia stem cells

15:50-16:05 Break 15min

16:05–16:30 Lecture 31 Kyeong Kyu Kim (SBRI, SKKU)

Ubiqutin and deubiquitinating enzymes: implication in cancer

16:30–16:55 Lecture 32 Junho Lee (IMBG, SNU)

Telomere maintenance through recruitment of internal genomic regions

17:00-19:00 Campus tour

19:00–21:30 Dinner + Best presentation awards

Outline of special workshop

November 14 (Sat)     

9:00–9:05 Opening remark by Drs. Ecomono/ Yazaki-Sugiyama

Session “Evolution and Ecology” Chair: Dr. Evan Ecomono

9:10–9:50 S-Lecture 1 (Evan Economo, OIST)

Global patterns of diversity and diversification rate in ants

9:50–10:40 S-Lecture 2 (Kenji Matsuura, Kyoto Univ)

Evolution of reproductive systems and pheromone communication in termites

10:40–11:00 Break 20 min

11:00–11:50 S-Lecture 3 (Yoh Iwasa, Kyusyu Univ)

Rate of species creation by geographic isolation and recurrent migration

12:00– 13:30 Lunch

Session “Neuroscience” Chair: Dr. Yoko Yazaki-Sugiyama

13:30–14:10 S-Lecture 4 (Yoko Yazaki-Sugiyama, OIST)

Memory formation of auditory experience for vocal learning in early developmental period in zebra finch

14:10–15:00 S-Lecture 5 Minmin Luo (NIBS, Beijing, China)

Reward Processing by the Dorsal Raphe

15:00-15:20 Break 20 min

15:20–16:10 S-Lecture 6 Yumiko Yoshimura (NIPS, Japan)

Experience-dependent maturation of fine-scale networks and feature-selective synchronization in visual cortex

16:10–17:00 S-Lecture 7 Tomoyuki Takahashi (OIST) 

Strength and precision of neurotransmission at mammalian presynaptic terminals and their postnatal developmental changes

17:00–17:10 Closing remark by Dr. Yamamoto

18:00–18:30 Move to the Seaside house

19:00–21:30 Farewell party (the Seaside house)

November 15 (Sun)

Departure (Optional Excursion to Shuri Castle)