Program
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Participant Institutes
- Institute of Biochemistry and Molecular Biology, National Taiwan University (IBMB, NTU)
- Institute of Molecular Biology and Genetics, Seoul National University (IMBG, SNU)
- Institute of Medical Science, University of Tokyo (IMSUT)
- Institute for Virus Research, Kyoto University (IVR, Kyoto Univ.)
- Okinawa Institute of Science and Technology Graduate University (OIST)
- Samsung Biomedical Research Institute, Sungkyunkwan University (SBRI, SKKU)
- Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (SIBCB, CAS)
- Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University (SIMS, SCHU)
Venue: OIST campus, B250
November 10 (Tue)
Arrivals
November 11 (Wed)
9:00-9:10 Opening remark: Dean of Research (George Iwama)
9:10-9:20 Information by Ichiro Masai
Session “Developmental Biology, signaling and disease model” Chair: Ichiro Masai
9:20–9:45 Lecture 1 Ichiro Masai (OIST)
Cell division and cadherin-mediated cell adhesion regulate lens epithelial cell movement in zebrafish
9:45–10:10 Lecture 2 Chan-Yen Ou (IBMB, NTU)
Cyclin-dependent kinases pathways regulate synapse formation in motor neurons
10:10–10:30 Break 20 min
10:30–10:55 Lecture 3 Yen-Shou Lin (IBMB, NTU)
Herbal medicines for ameliorating the Aβ-induced depolarization in primary cortical neurons
10:55–11:20 Lecture 4 Hsiu-Mei Hsieh (IBMB, NTU)
Identification of nature products to ameliorate learning memory deficit in streptozotocin-induced Alzheimer mouse model
11:20–11:45 Lecture 5 Jun-ichiro Inoue (IMSUT)
Regulation of the TRAF6-NF-B and the Calcineurin-NFATc1 pathways in RANK signal-induced osteoclastogenesis
12:00–13:30 Lunch
12:00–13:00 DIRECTOR MEETING (C016, Lab1)
Session “Gene regulation and genetics, ecology” Chair: Hidetoshi Saze
13:30–13:55 Lecture 6 Jeong Hoon Kim (SBRI, SKKU)
DBC1, a master regulator of β-catenin-PROX1 signaling axis
13:55–14:20 Lecture 7 Masaki Takahashi (IMSUT)
Development of an efficient Cell-SELEX using engineered isogenic cell lines to generate RNA aptamers against a cell surface protein of interest
14:20–14:45 Lecture 8 Yu-Feng Hsu (IBMB, NTU)
Diversity of phytophagous insects associated with Fagus hayatae forest
14:45–14:55 Break 10 min
Session “Structural Biology” Chair: Matthias Wolf
14:55–15:20 Lecture 9 Matthias Wolf (OIST)
Cryo-EM imaging with the Volta Phase Plate
15:20-15:45 Lecture 10 Bo OuYang (SIBCB, CAS)
NMR applications on mitochondrial carrier machinery
15:45–16:00 Break 15 min
Young investigator talk: Chair: Matthias Wolf, Ichiro Masai
“Developmental Biology and signaling”
16:00–16:10 short talk 1 (P-1) Kumiko Kobayashi (IVR, Kyoto Univ.)
Single-cell analysis of mouse segmentation clock
16:10–16:20 short talk 2 (P-2) Yi-Jyun Luo (OIST)
The Lingula genome and the patterning of BMP-chordin axis in brachiopods
16:20–16:30 short talk 3 (P-3) Shin Jeon (IMBG, SNU)
Anteroposterior limb skeletal patterning requires the bifurcating function of SWI/SNF chromatin remodeling complex in Hedgehog pathway
16:30–16:40 short talk 4 (P-4) Young-Eun Leem (SBRI, SKKU)
PRMT7 deficiency enhances adipogenesis leading to obesity-related phenotypes in mice
16:40–16:50 short talk 5 (P-5) Sang A Lee (SIMS, SCHU)
miR-31/SDHA axis regulates reprograming efficiency through mitochondrial metabolism
16:50–17:05 Break 15min
17:05–17:15 short talk-6 (P-6) Se-Hyuk Kim (SBRI, SKKU)
SSU72 functions as a gatekeeper monitoring for chromosome integrity
17:15–17:25 short talk 7 (P-7) Chia-Wei Lin (IBMB, NTU)
Investigation of the molecular pathogenesis for SCA17 through transgenic mouse model
17:25–17:35 short talk-8 (P-8) Sungho Hong (OIST)
GABA-mediated phase repulsive coupling and seasonal time coding in the suprachiasmatic nucleus
“Structural biology”
17:35–17:45 short-talk 9 (P-9) Yukihiko Sugita (OIST)
Cryo-electron microscopic analysis of influenza virus ribonucleoprotein complex during transcription
17:45–17:55 short talk 10 (P-10) Hong-Wen Chen (SIBCB, CAS)
Structural Basis of Telomerase Recruitment in Yeast
17:55-18:10 Break 15min
“Gene regulation and genetics, ecology”
18:10–18:20 short talk 11 (P-11) Eun Ji Yu (SBRI, SKKU)
Positive regulation of β-catenin-PROX1 signaling axis by DBC1 in colon cancer progression
18:20–18:30 short talk 12 (P-12) Imchang Lee (IMBG, SNU)
OrthoANI: An improved algorithm and software for genome-based species definition of Bacteria and Archaea
18:30–18:40 short talk 13 (P13) Jia-Yuan Liang (IBMB, NTU)
Systematics and Biology of Clearwing Moths - The Synanthedonini Tribe in Taiwan
“Cancer biology”
18:40–18:50 short talk 14 (P-14) Yukino Machida (IMSUT)
Maintenance of stemness of breast cancer by FRS2beta, a feedback inhibitor for HER, during tumorigenesis
18:50–19:00 short talk 15 (P-15) Zhixin Qiu (SIBCB, CAS)
Modeling liver cancer using cancer cell lines to guide the precision medicine for liver cancer
19:00–19:10 short talk 16 (P-16) Shuto Hayashi (IMSUT)
A Bayesian Method for HLA genotyping from Whole Genome Sequencing Data
19:30–21:30 Dinner + Poster session (Cafeteria level B)
November 12 (Thu)
Session “Cell Biology” Chair: Tadashi Yamamoto
9:00–9:25 Lecture 11 Jae Bum Kim (IMBG, SNU)
Fat Tissue Dysregulation and Insulin Resistance in Obesity
9:25–9:50 Lecture 12 Jaeseok Han (SIMS, SCHU)
Disturbance of ER homeostasis and oxidative stress synergizes to cause cell death
9:50–10:15 Lecture 13 Tadashi Yamamoto (OIST)
mRNA decay machinery and its physiological roles
10:15–10:35 Break 20 min
10:35–11:00 Lecture 14 Yuri Shibata (IMSUT)
The role of polyubiquitin chains in HTLV-1 Tax-induced IKK activation
11:00–11:25 Lecture 15 Yong Tae Kwon (IMBG, SNU)
Modulation of autophagy by the N-end rule proteolytic system: its role in protein quality control and innate immunity
11:25–11:50 Lecture 16 Gang Wang (SIBCB, CAS)
The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination
12:00–13:30 Lunch
Chair by Hidetoshi Saze
13:30–13:55 Lecture 17 Jeong Kyo Yoon (SIMS, SCHU)
Regulatory role of R-spondin-LGR4 signaling in skeletal muscle stem cell and myogenic differentiation
Session “Virology and Immunology-1” Chair: Hiroki Ishiwaka
13:55–14:20 Lecture 18 Ping Hu (SIBCB, CAS)
Acute inflammation is required for muscle regeneration
14:20–14:45 Lecture19 Kae Won Cho (SIMS, SCHU)
Adipose Tissue Immune cells: Key players in metabolicsyndromes
14:45–15:10 Lecture 20 Tae Jin Kim (SBRI, SKKU)
Development of Putative B-1 helper T cells
15:10–15:30 Break 20 min
Young investigator talk: Chair: Hiroki Ishiwaka, Hidetoshi Saze
“Cell Biology”
15:30–15:40 short talk 17 (P-17) Koichiro Akiyama (IVR, Kyoto Univ.)
Analysis of the conserved membrane-reentrant loop of RseP, an intramembrane-cleaving protease
15:40–15:50 short talk 18 (P-18) Megumi Ikeda (IVR, Kyoto Univ.)
Dormant cells emerging from Embryonic Stem Cells sustain pluripotency in differentiation condition
15:50–16:00 short talk 19 (P-19) Shibin Hu (SIBCB, CAS)
Protein arginine methyltransferase CARM1 attenuates the paraspeckle mediated nuclear retention of mRNAs containing IRAlus
16:00–16:10 short talk 20 (P-20) Lidya Kristiani (SIMS, SCHU)
Development of High Sensitive (HS) Hi-C Method through Adaptor-Mediated Ligation and Low Density DNA Digestion
16:10–16:20 short talk 21 (P-21) Jiho Park (IMBG, SNU)
Study on the function of BubR1 in zebrafish model system
16:20-16:35 Break 15 min
16:35–16:45 short talk 22 (P-22) Moe Matsushita (IMSUT)
Identification of a novel redox-sensor that mediatesactivation of stress-responsive MAPK pathways
16:45–16:55 short talk 23 (P-23) Debojyoti De (SBRI, SKKU)
Developing an efficient and selective strategy for differentiating pluripotent stem cells
“Virology and Immunology”
16:55–17:05 short talk 24 (P-24) Taku Kureha (OIST)
CNOT3 is important for thymocyte development throughthe regulation of TCR-mediated cell death signaling
17:05–17:15 short talk 25 (P-25) Dongming Zhao (IMSUT)
Characterization of a reporter-expressing H5N1 influenza A virus in vitro and in vivo
17:15–17:25 short talk 26 (P-26) Xiangpeng Sheng (SIBCB, CAS)
An Escherichia coli O157:H7 effector inhibits host inflammation response by ubiquitylating TRAFs family
17:25-17:40 Break 15 min
“Developmental biology and Disease model”
17:40–17:50 short talk 27 (P-27) Ji Hye Park (SBRI, SKKU)
Protein kinase B/Akt phosphorylates Histone 2A, controlling neuronal apoptosis under oxidative stress
17:50–18:00 short talk 28 (P-28) Jie Yin (SIBCB, CAS)
A secreted protein plays a key role in regulating aging related muscle atrophy
18:00–18:10 short talk 29 (P-29) Lesly Puspita (SIMS, SCHU)
In vitro disease modeling study with patient iPSc suggested metabolic impairment of Parkinson disease
18:10–18:20 short talk 30 (P-30) Mona Fendereski (SIMS, SCHU)
Directed in vitro myogenesis of human embryonic stem cells and their in vivo delivery using biomimetic materials
18:20-18:35 Break 15 min
18:35–18:45 short talk 31 (P-31) Altanbyek Volodya (SIMS, SCHU)
The imbalance of mitochondrial dynamics in ALS
18:45–18:55 short talk 32 (P-32) Su Jin Ham (IMBG, SNU)
Regulation of Parkin E3 ligase by its own UBL domain
18:55–19:05 short talk 33 (P-33) He-Pei Yu (IBMB, NTU)
Identifying a novel compound NCT016 as an anti-Alzheimer’s disease agent
19:30–21:30 Dinner + Poster session (Cafeteria level B)
November 13 (Fri)
Session “Virology and Immunology-2” Chair: Hiroki Ishikawa
9:00–9:25 Lecture 21 Hiroki Ishikawa (OIST)
HLX1 regulates differentiation and function of CD4 T helper cells
9:25–9:50 Lecture 22 Ichiro Taniguchi (IVR, Kyoto Univ.)
HIV-1 Rev protein specifies the viralRNA export pathway by suppressing TAP/NXF1 recruitment
9:50–10:15 Lecture 23 Fajian Hou (SIBCB, CAS)
An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response
10:15–10:45 Break 30 min
10:45–11:10 Lecture 24 Satoshi Fukuyama (IMSUT)
Generation of Color-flu for in vivo imaging of influenza virus infection
11:10–11:35 Lecture 25 Jun-ichirou Yasunaga (IVR, Kyoto Univ.)
Multimodal functions of HTLV-1 bZIP factor as RNA and protein on proliferation and survival of CD4+ T cells
11:40–12:00 Group Photo
12:00– 13:30 Lunch
“Session “Cancer Biology” Chair: Sumiko Watanabe
13:30–13:55 Lecture 26 Seiya Imoto (IMSUT)
Challenges for genomic big data analysis in IMSUT
13:55–14:20 Lecture 27 Seongho Ryu (SIMS, SCHU)
The role of PRC2 in cancer stem cell maintenance
14:20-14:45 Lecture 28 Chin Ha Chung (IMBG, SNU)
UFM1 in the Control of Breast Cancer Development
14:45-15:00 Break 15 min
15:00–15:25 Lecture 29 Hyeon Ho Kim (SBRI, SKKU)
Neurofibromin 2 (NF2) controls the invasiveness of glioblastoma
15:25–15:50 Lecture 30 Susumu Goyama (IMSUT)
The role of thrombin-Par-1 pathway in myeloid leukemia stem cells
15:50-16:05 Break 15min
16:05–16:30 Lecture 31 Kyeong Kyu Kim (SBRI, SKKU)
Ubiqutin and deubiquitinating enzymes: implication in cancer
16:30–16:55 Lecture 32 Junho Lee (IMBG, SNU)
Telomere maintenance through recruitment of internal genomic regions
17:00-19:00 Campus tour
19:00–21:30 Dinner + Best presentation awards
Outline of special workshop
November 14 (Sat)
9:00–9:05 Opening remark by Drs. Ecomono/ Yazaki-Sugiyama
Session “Evolution and Ecology” Chair: Dr. Evan Ecomono
9:10–9:50 S-Lecture 1 (Evan Economo, OIST)
Global patterns of diversity and diversification rate in ants
9:50–10:40 S-Lecture 2 (Kenji Matsuura, Kyoto Univ)
Evolution of reproductive systems and pheromone communication in termites
10:40–11:00 Break 20 min
11:00–11:50 S-Lecture 3 (Yoh Iwasa, Kyusyu Univ)
Rate of species creation by geographic isolation and recurrent migration
12:00– 13:30 Lunch
Session “Neuroscience” Chair: Dr. Yoko Yazaki-Sugiyama
13:30–14:10 S-Lecture 4 (Yoko Yazaki-Sugiyama, OIST)
Memory formation of auditory experience for vocal learning in early developmental period in zebra finch
14:10–15:00 S-Lecture 5 Minmin Luo (NIBS, Beijing, China)
Reward Processing by the Dorsal Raphe
15:00-15:20 Break 20 min
15:20–16:10 S-Lecture 6 Yumiko Yoshimura (NIPS, Japan)
Experience-dependent maturation of fine-scale networks and feature-selective synchronization in visual cortex
16:10–17:00 S-Lecture 7 Tomoyuki Takahashi (OIST)
Strength and precision of neurotransmission at mammalian presynaptic terminals and their postnatal developmental changes
17:00–17:10 Closing remark by Dr. Yamamoto
18:00–18:30 Move to the Seaside house
19:00–21:30 Farewell party (the Seaside house)
November 15 (Sun)
Departure (Optional Excursion to Shuri Castle)