Seminar "Modelling protein search on human DNA" by Prof. Ludvig Lizana
- Date: Wed, May 22nd
- Time: 10:30-11:30
- Venue: C016-Lab1
- Speaker: Ludvig Lizana, Senior Lecturer (associate professor) at Department of Physics, Umea University.
Modelling protein search on human DNA
To turn on a gene, a protein has bind to a specific site on DNA. However, as DNA is long, this binding site is just one out of hundreds of million of others. How can a few proteins find the correct site in a reasonable amount of time? In this talk, I will lay out the protein-search problem in cells, formulate a model, and compare some of the model’s outcomes to data for active genes.