Publications

 

Peer-reviewed primary publications  (corresponding author)

Osabe K, Harukawa Y, Miura S, Saze H. (2017). Epigenetic Regulation of Intronic Transgenes in Arabidopsis. Sci Rep. Mar 24;7:45166. doi: 10.1038/srep45166.

Ito H, Kim JM, Matsunaga W, Saze H, Matsui A, Endo TA, Harukawa Y, Takagi H, Yaegashi H, Masuta Y, Masuda S, Ishida J, Tanaka M, Takahashi S, Morosawa T, Toyoda T, Kakutani T, Kato A, Seki M. (2016). A Stress-Activated Transposon in Arabidopsis Induces Transgenerational Abscisic Acid Insensitivity. Sci Rep. 6:23181. doi: 10.1038/srep23181.

Ito T, Tarutani Y, To TK, Kassam M, Duvernois-Berthet E, Cortijo S, Takashima K, Saze H, Toyoda A, Fujiyama A, Colot V, Kakutani T. (2015). Genome-wide negative feedback drives transgenerational DNA methylation dynamics in Arabidopsis. PLoS Genet. 11(4):e1005154.

Le ​Tu N.Miyazaki Y., Takuno S.,  Saze H. (2015). Epigenetic regulation of intragenic transposable elements impacts gene transcription in Arabidopsis thaliana. Nucleic Acids Res., doi: 10.1093/nar/gkv258

Saze H., Kitayama J, Takashima K, Miura S, Harukawa Y, Ito T, Kakutani T. (2013). Mechanism for full-length RNA processing of Arabidopsis genes containing intragenic heterochromatin. Nat Commun., 4:2301.

Sasaki T, Kobayashi A, Saze H, Kakutani T. (2012) RNAi-independent de novo DNA methylation revealed in Arabidopsis mutants of a chromatin remodeling gene DDM1. Plant J., 70(5): 750-758.

Inagaki S, Miura-Kamio A, Nakamura Y, Lu F, Cui X, Cao X, Kimura H, Saze H, Kakutani T. (2010). Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome. EMBO J., 29(20):3496-506.

Miura, A., Nakamura, M., Inagaki, S., Kobayashi, A., Saze, H., and Kakutani, T. (2009). An Arabidopsis jmjC domain protein protects transcribed genes from DNA methylation at CHG sites. EMBO J., 28, 1078-1086.

Saze, H., Shiraishi, A., Miura, A., and Kakutani, T. (2008). Control of genic DNA methylation by a jmjC-domain containing protein in Arabidopsis thaliana. Science, 319, 462-465.

Saze, H., and Kakutani, T. (2007). Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1. EMBO J., 26, 3641-3652.

Kinoshita, Y., Saze, H., Kinoshita, T., Miura, A., Soppe, W., Koornneef, M., and Kakutani, T. (2007). Control of FWA gene silencing in Arabidopsis thaliana by SINE-related dirct repeats. Plant J., 49, 38-45.

Tariq, M., Saze, H., Probst, A., Lichota, J., Habu, Y., and Paszkowski, J. (2003). Erasure of CpG methylation in Arabidopsis alters patterns of histone H3 methylation in heterochromatin. Proc. Natl. Acad. Sci. USA, 100, 8823-8827.

Saze, H., Mittelsten-Scheid, O., and Paszkowski, J. (2003). Maintenance of CpG methylation is essential for epigenetic inheritance during plant gametogenesis. Nat Genet., 34, 65-69.

Saze, H., Ueno, Y., Hisabori, T., Hayashi, H., and Izui, K. (2001). Thioredoxin-mediated reductive activation of a protein kinase for the regulatory phosphorylation of C4-form Phosphoenolpyruvate Carboxylase from Maize. Plant Cell Physiol., 42, 1295-1302.

 

Other Publications

(Review) Saze H. (2018). Epigenetic regulation of intragenic transposable elements: a two-edged sword
J Biochem. 164 (5), 323-328

(Review) Espinas NASaze H, Saijo Y. (2016). Epigenetic Control of Defense Signaling and Priming in Plants. Front Plant Sci. 2016 Aug 11;7:1201. doi: 10.3389/fpls.2016.01201.

(Review) To TK, Saze H, Kakutani T. (2015). DNA Methylation within Transcribed Regions. Plant Physiol., 168(4):1219-25. doi: 10.1104/pp.15.00543. Epub 2015 Jul 4.

(Review) Saze, H. (2012). Transgenerational Inheritance of Induced Changes in the Epigenetic State of Chromatin in Plants. Genes Genet Systems,  87(3): 145-52.

(Review) Saze, H, Tsugane K, Kanno T and Nishimura T. (2012). DNA Methylation in Plants: Relationship with Small RNAs and Histone Modifications, and Functions in Transposon Inactivation. Plant Cell Physiol., 53(5): 766-84.

(Review) Saze, H and Kakutani T. (2011) Differentiation of epigenetic modifications between transposons and genes. Curr Opin Plant Biol., 14(1):81-7.

(Review) Saze, H. (2008). Epigenetic Memory Transmission through Mitosis and Meiosis in Plants. Semin. Cell Dev. Biol. 19, 527-536.

(Review) Saze, H., Sasaki, T., and Kakutani, T. (2008). Negative Regulation of DNA Methylation in Plants. Epigenetics 3,122-124.