Hidetoshi Saze

  Professor 

BSc MSc (Kyoto University)  PhD (Universitat Basel)

Nationality

Japan

 

Awards

  • Genetics Society of Japan Young Investigator Award (2011)
  • Young Scientist’s Prize, Japan Ministry of Education, Culture, Sports, Science and Technology (2012)

 

Selected Publications

Berthelier J, Furci L, Asai S, Sadykova M, Shimazaki T, Shirasu K, Saze H. (2023) Long-read direct RNA sequencing reveals epigenetic regulation of chimeric gene-transposon transcripts in Arabidopsis thaliana. Nat Commun. Jun 5;14(1):3248. doi: 10.1038/s41467-023-38954-z.

Miryeganeh M, Marlétaz F, Gavriouchkina D, Saze H. De novo genome assembly and in natura epigenomics reveal salinity-induced DNA methylation in the mangrove tree Bruguiera gymnorhiza. New Phytol. 2022 Mar;233(5):2094-2110. doi: 10.1111/nph.17738. Epub 2021 Oct 16. PMID: 34532854

Le NT, Harukawa Y, Miura S, Boer D, Kawabe A, Saze H. (2020). Epigenetic regulation of spurious transcription initiation in Arabidopsis. Nat Commun. Jun 26;11(1):3224. doi: 10.1038/s41467-020-16951-w.

Espinas NA, Tu LN, Furci L, Shimajiri Y, Harukawa Y, Miura S, Takuno S, Saze H. (2020). Transcriptional regulation of genes bearing intronic heterochromatin in the rice genome. PLoS Genet. Mar 18;16(3):e1008637. doi: 10.1371/journal.pgen.1008637

Osabe K, Harukawa Y, Miura S, Saze H. (2017). Epigenetic Regulation of Intronic Transgenes in Arabidopsis. Sci Rep. Mar 24;7:45166. doi: 10.1038/srep45166.

Le ​Tu N., Miyazaki Y., Takuno S.,  Saze H. (2015). Epigenetic regulation of intragenic transposable elements impacts gene transcription in Arabidopsis thaliana. Nucleic Acids Res., doi: 10.1093/nar/gkv258

Saze H., Kitayama J, Takashima K, Miura S, Harukawa Y, Ito T, Kakutani T. (2013). Mechanism for full-length RNA processing of Arabidopsis genes containing intragenic heterochromatin. Nat Commun., 4:2301.

Saze, H., Shiraishi, A., Miura, A., and Kakutani, T. (2008). Control of genic DNA methylation by a jmjC-domain containing protein in Arabidopsis thaliana. Science 319, 462-465.

Saze, H. (2008). Epigenetic memory transmission through mitosis and meiosis in plants. Semin. Cell Dev. Biol. 19, 527-536.

Saze, H., and Kakutani, T. (2007). Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1. EMBO J. 26, 3641-3652.

Saze, H., Mittelsten-Scheid, O., and Paszkowski, J. (2003). Maintenance of CpG methylation is essential for epigenetic inheritance during plant gametogenesis. Nat. Genet. 34, 65-69.