Principal Investigator
Ye Zhang (Assistant Professor)
B.S. Nankai University
Ph.D. Hong Kong University of Science and Technology
ye.zhang@oist.jp
Professional Experience
- Postdoc Fellow, University of Turin, Italy
- Postdoc Fellow, Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland
- Visiting Scholar, Norwegian University of Science and Technology (NTNU), Norway
- Postdoc Associate, Brandeis University, USA
Invited talks
- The 11th Chinese National Conference on Chemical Biology, Chinese Chemical Society (November, 2019)
- 70th Anniversary of the Division Meeting of Division of Colloid and Surface Chemistry, The Chemistry Society of Japan (November, 2019)
- The SPIRITS International Symposium--Kyoto University, Japan (March, 2019) 'Regulate Hippo signaling via lipid-raft-targeted molecular assembly for ovarian cancer treatment'
- School of Chemistry, Sun Yat-sen University, China (November, 2018) 'Control of the tumorigenic signaling pathway via membrane-protein-targeted peptide assembly'
- Institute of Biochemistry and Cell Biology (IBCB), SIBS, CAS, China (September, 2018) 'Control of the tumorigenetic signaling pathway via assembly of integrin-targeted synthetic peptides'
- IMCE International Symposium--Kyushu University, Japan (March, 2018) 'Regulate Cancer Cell Mechanics by Synthetic Molecular Self-assembly'
- 24rd EAJS--Kyoto University, Japan (October, 2017) 'Tie up cytoskeleton to inhibit ovarian cancer metastasis'
Select Publications
Patent
- Zhang, Y.; Xu, B. “Polymeric Materials Having Active Cross-linkers, Methods for Making Them, and Use Thereof” US Patent 43022.0100.
Book Chapter
- Zhang, Y.; Xu, B.* “Superactivity of Enzymes in Supramolecular Hydrogels” in Proteins in Solution and at Interfaces: Methods and Applications in Biotechnology and Materials Science. Wiley, 2013, ISBN: 9780470952511
Selected Journal Article
- Wei Ji, Shijin Zhang, Sachie Yukawa, Shogo Onomura, Toshio Sasaki, Kun'ichi Miyazawa, and Ye Zhang.* "Regulate Higher-order Organization through the Synergy of Two Self-sorted Assemblies" Angew. Chem. Int. Ed. 2018, 57, 3636-3640
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Guanying Li, Toshio Sasaki, Shunsuke Asahina, Michael C. Roy, Toshiaki Mochizuki, Koji Koizumi and Ye Zhang.* “Patching of Lipid Rafts by Molecular Self-Assembled Nanofibrils Suppresses Cancer Cell Migration” Chem. 2017, 2, 283-298.
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Qingcong Wei, Mengchi Xu, Chuanan Liao, Qing Wu, Mingyu Liu, Ye Zhang,* Chengtie Wu,* Liming Cheng and Qigang Wang.* "Printable hybrid hydrogel by dual enzymatic polymerization with superactivity" Chemical Science, 2016, 7, 2748.
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Zhang, Y.; Zhou, N.; Shi, J. F.; Pochapsky, S. S.; Pochapsky, T. C.; Zhang, B.; Zhang, X. X.; Xu, B.* “Unfolding a molecular trefoil derived from a zwitterionic metallopeptide to form self-assembled nanostructures” Nature Commun. 2015, 6, 6165.
- Zhang, Y.; Zhou, N.; Kim, D.; Fraden, S.*; Epstein, I. R.*; Xu, B.* “ Giant Volume Change of Active Gels under Continuous Flow” J. Am. Chem. Soc., 2014, 136, 7341-7347.
- Zhang, Y.; Zhou, N.; Akella, S.; Kuang, Y.; Kim, D.; Schwartz, A.; Bezpalko, M.; Foxman, B. M.; Fraden, S.; Epstein, I. R.*; Xu, B.* “ Active Hyper Crosslinkers Confer Active Gels” Angew. Chem. Int. Ed. 2013, 52, 6944-6948.
- Zhang, Y.; Zhang, B.; Kuang, Y.; Gao, Y.; Shi, J.; Zhang, X. X.; Xu, B.* “A Redox Responsive, Fluorescent Supramolecular Metallohydrogel Consists of Nanofibers with Single-Molecule Width” J. Am. Chem. Soc., 2013, 135, 5008-5011.
- Zhang, Y.; Li, N.; Delgado, J.; Gao, Y.; Kuang, Y.; Fraden, S.; Epstein, I. R.*; Xu, B.* “Post-Self-Assembly Crosslinking of Molecular Nanofibers for Oscillatory Hydrogels” Langmuir, 2012, 28, 3063-3066.
- Zhang, Y.; Kuang, Y.; Gao, Y.; Xu, B.* “Versatile Small Molecule Motifs for Self-assembly in Water and Formation of Biofunctional Supramolecular Hydrogels” Langmuir, 2011, 27, 529-537.