David Van Vactor

  Visiting Professor 

BA (Johns Hopkins),  PhD (UCLA)



Research Career

  • UC Berkeley
  • Woods Hole Oceanographic Institution - Marine Biology Laboratory
  • Harvard Medical School - Dept. of Cell Biology

Selected Publications

1) McNeill, E. and Van Vactor, D. (2012) microRNAs Shape the Neuronal Landscape. Neuron, 75(3): 363-379.

2) Lu, C.S. and Van Vactor, D. (2013) Genetic Analysis of Synaptogenesis in Cellular Migration and Formation of Neuronal Connections: Comprehensive Developmental Neuroscience, Volume 2.  Elsevier Ltd., London, UK.

3) Li, W., Cressy, M., Qin, H., Fulga, T., Van Vactor, D. and Dubnau, J.  (2013) microRNA-276a Functions in Ellipsoid Body and Mushroom Body Neurons for Naive and Conditioned Olfactory Avoidance in Drosophila. J. Neuroscience, 33(13):5821-5833.

4) Sen, A., Dimlich, D., Guruharsha, K. G., Kankel, M.W., Hori, K., Yokokura, T., Brachat, S., Richardson, D., Loureiro, J., Sivasankaran, R., Curtis, D., Davidow, L., Rubin, L., Hart, A., Van Vactor, D. and Artavanis-Tsakonas. S. (2013) The genetic circuitry of Survival Motor Neuron, the gene underlying Spinal Muscular Atrophy. PNAS plus, 110(26):E2371-80.

5) Amaral, A., Brito, B., Yokokura, T., Van Vactor, D.  and Gama-Carvalho, M. (2014) Quality assessment and control of tissue specific RNA-seq libraries of Drosophila transgenic RNAi models. Frontiers in Genetics Research Topics, 5:43.

6) Loya, C.M., Elizabeth M. McNeill, E.M., Bao, H., Zhang, B. and Van Vactor, D. (2014) MiR-8 Regulates Postsynaptic Structure and the Actin Cytoskeleton through Repression of Enabled. Development, 141(9):1864-74.

7) Cecilia S. Lu, Bo Zhai, Alex Mauss, Matthias Landgraf, Steven Gygi and David Van Vactor (2014) microRNA-8 Promotes Axon Targeting Via Coordinate Regulation of Cell Adhesion Molecules During Motor Axon Targeting. Philosophical Transactions of the Royal Society B, 369(1652). pii: 20130517.

8) Fulga, T.A, McNeill, E.M., Binari, R., Yelick, J., Blanche, A., Booker, M., Schnall-Levin, M., Zhao, Y., DeLuca, T., Bejarano, F., Han, Z., Lai,  E.C., Wall, D.P., Perrimon, N. and Van Vactor, D. (2015) A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs. Nature Communications, 6:7279.

9) Virginia Guarani, Elizabeth M. McNeill, Joao A. Paulo, Edward L. Huttlin, Florian Fröhlich, Steven P. Gygi, David Van Vactor and J. Wade Harper. (2015) QIL1 is a Novel Mitochondrial Protein Required for MICOS Complex Stability and Cristae Morphology. eLife, 4. doi: 10.7554/eLife.06265.

10) Van Vactor, D. and Sigrist, S. (2017) Presynaptic Morphogenesis, Active Zone Organization and Structural Plasticity in Drosophila. Current Opinion in Neurobiology, in press.