Survey the molecular biology of the cell, the universal biochemical mechanisms at the heart of all living organisms, through lectures based on the classic text by Alberts et al. Working through research-based problem sets, explore the cell and its components and constituents from the level of individual molecules to their interaction, dynamics and control at the cellular and intercellular level. Classroom discussions explore new findings that may challenge previous conclusions.
- Cells and Genomes
- Cell Chemistry and Bioenergetics
- Proteins
- DNA, Chromosomes, and Genomes
- DNA Replication, Repair, and Recombination
- How Cells Read the Genome: From DNA to Protein
- Control of Gene Expression
- Examination 1
- Analyzing Cells, Molecules, and Systems
- Visualizing Cells
- Membrane Structure
- Membrane Transport of Small Molecules and the Electrical Properties of Membranes
- Intracellular Compartments and Protein Sorting
- Intracellular Membrane Traffic
- Energy Conversion: Mitochondria and Chloroplasts
- Cell Signaling
- The Cytoskeleton
- The Cell Cycle
- Cell Death
- Examination 2
- Cell Junctions and the Extracellular Matrix
- Cancer
- Development of Multicellular Organisms
- Stem Cells and Tissue Renewal
- Pathogens and Infection
- The Innate and Adaptive Immune Systems
- Examination 3
Prof Kono is available Fridays for questions and consultation.
Three small examinations will be required during the term, weighted 25%, 25%, and 50%.
The first two exams cover material up to that time. The final exam covers all material of the term.
Grade expectations are
A corresponds to scores of 85-100%
B corresponds to scores of 70-84%
C corresponds to scores of 60-69%
Scores less than 60% receive a fail grade.
- Molecular Biology of the Cell, 6th Edition, by Bruce Alberts et al.
- The Problems Book: for Molecular Biology of the Cell 6th Edition, by Tim Hunt and John Wilson