B06
Course Coordinator: 
Mitsuhiro Yanagida
Cell Biology and Genetics
Description: 

Molecular cell biology is a vast and growing field, and this course covers the essential principles required to understand the regulation and functioning of the living and dying cell, the fundamental unit of life. Lectures cover classical and molecular genetics, including genetic regulation and mRNA, before moving on to describe the physical and chemical organization of the cell, and the way these various domains interact in the normal cell.

Aim: 
This course provides an overview of the principles of genetics, molecular and cell biology to students
Detailed Syllabus: 
  1. Mendelian genetics
  2. Recombination, linkage and mapping
  3. Gene interaction, complementation, and epistasis
  4. Nucleic acids and chromosome structure
  5. Protein structure and function
  6. DNA replication
  7. Transcription and its regulation
  8. mRNA splicing and translation 
  9. Maintenance of genomic integrity 
  10. Cellular structures and organelles 
  11. Intracellular membrane trafficking 
  12. Cell cycle and cell division 
  13. Cellular cytoskeleton and cell movement 
  14. Cell-cell communication 
  15. Apoptosis
Course Type: 
Elective
Credits: 
2
Assessment: 
Reports on various topics through the term.
Text Book: 
Molecular Biology of the Cell 5 edn Alberts, Johnson, Lewis, Raff, Roberts, and Walter. (2007) Garland
Molecular Biology of the Gene 6 edn Watson Baker Bell Gann (2007) Benjamin Cummings
Reference Book: 
Molecular Cell Biology 6 edn, Lodish et al., (2007) WH Freeman
Lewin’s Genes X, Krebs, Goldstein, Kilpatrick (2009) Jones & Bartlett
Recombinant DNA: Genes and Genomes, 3 edn, Watson, Myers, Caudy, Witkowski (2007) WH Freeman
Mitosis: methods and protocols, Andrew D McAinsh (2009)Humana Press