Peer reviewed research articles:

Ananda Babu L.P, Wang H.Y., Eguchi K., Guillaud L., Takahashi T. (2020) Microtubule and actin differentially regulate synaptic vesicle cycling to maintain high-frequency neurotransmission. J. Neurosci. 40, 131-142.

Yamashita M., Kawaguchi S., Hori T., Takahashi T. (2018) Vesicular GABA uptake can be rate limiting for recovery of IPSCs from synaptic depression. Cell Rep. 22, 3134-3141.

Eguchi K., Taoufiq Z., Thorn-Seshold O., Trauner D., Hasegawa M., Takahashi T. (2017) Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of Held. J. Neurosci. 37, 6043-6052.

Guillaud L., Dimitrov D., Takahashi T. (2017) Presynaptic morphology and vesicular composition determine vesicle dynamics in mouse central synapses.  eLife 6: e24845.

Takami C., Eguchi K., Hori T., Takahashi T. (2017) Impact of vesicular glutamate leakage on synaptic transmission at the calyx of Held. J. Physiol. 595: 1263-1271.

Dimitrov D., Takagi H., Guillaud L., Saitoh N., Eguchi K., Takahashi T. (2016) Reconstitution of giant mammalian synapses in culture for functional and imaging studies. J. Neurosci. 36, 3600-3610.

Nakamura Y., Harada H., Kamasawa N., Matsui K., Rothman J.S., Shigemoto R., Silver R.A., DiGregorio D.A., Takahashi T. (2015) Nanoscale distribution of presynaptic Ca2+channels and its impact on vesicular release during development. Neuron. 85, 145-158.

Takafumi M., Hirokazu H., Takahashi T. (2013) Activity-dependent neurotrophin signaling underlies developmental switch of Ca2+ channel subtypes mediating neurotransmitter release. J. Neurosci. 27, 18755-18763.

Taoufiq Z.*, Eguchi K.*, Takahashi T. (2013) Rho-kinase accelerates synaptic vesicle endocytosis by linking cyclic GMP-dependent protein kinase activity to phosphatidylinositol-4,5-bisphosphate synthesis. J. Neurosci. 33, 12099-12104. *Co-first authors

Hori T. and Takahashi T. (2012) Kinetics of synaptic vesicle refilling with neurotransmitter glutamate. Neuron 76, 511-517.

Eguchi K., Nakanishi S., Takagi H., Taoufiq Z., Takahashi  T. (2012) Maturation of a PKG-dependent retrograde mechanism for exo-endocytic coupling of  synaptic vesicles. Neuron 74, 517-529.

Yamashita T., Eguchi K., Saitoh N., von Gersdorff H., Takahashi T. (2010). Developmental shift to a mechanism of synaptic vesicle endocytosis requiring nanodomain Ca2+. Nat. Neurosci. 13, 838-844.

Watanabe H., Yamashita T., Saitoh N., Kiyonaka S., Iwamatsu A., Campbell K.P., Mori Y., Takahashi T. (2010). Involvement of Ca2+ channel synprint site in synaptic vesicle endocytosis. J. Neurosci. 30, 655-660.


Review articles:

Takahashi T. (2015). Strength and precision of neurotransmission at mammalian presynaptic terminals. Proc Japan Acad, Ser B 91, 305-320.

Takahashi T. (2005). Postsynaptic receptor mechanisms underlying developmental speeding of synaptic transmission. Neuroscience Res. 53, 229-240.

Takahashi T. (2005). Dynamic aspects of presynaptic calcium currents mediating synaptic transmission. Cell Calcium 37, 507-511.

Takahashi T., Kajikawa Y., Kimura M., Saito N. & Tsujimoto T. (2004). Presynaptic mechanism underlying regulation of transmitter replase by G protein coupled receptors. Korean J. Physiol. Pharmacol. 8, 69-76.

Otsuka M.and  Takahashi T. (1977). Putative peptide neurotransmitters. Ann. Rev. Pharmacol. Toxicol.17, 425-439.



Dimitrov D., Guillaud L., Eguchi K., Takahashi T. (2018) Culture of Mouse Giant Central Nervous System Synapses and Application for Imaging and Electrophysiological Analyses. In: Skaper S. (eds) Neurotrophic Factors. Methods in Molecular Biology, vol 1727, 201-215.