1. Xunwu Hu, Ye Zhang*. "Developing Biomaterials to Mediate the Spatial Distribution of Integrin" Biophysics Reviews, 2021, 2 041302 (invited review). 


  2. Dingze Mang+, Sona Rani Roy+,  Qizheng Zhang+, Xunwu Hu, Ye Zhang*. "Heparan-Sulfate-Instructed Self-Assembly Selectively Inhibits Cancer Cell Migration" ACS Applied Materials & Interfaces, 2021, 13, 17236-17242. (+ These authors contributed equally to this work). 

  3. Guanying Li+, Xunwu Hu+,  Xia Wu, Ye Zhang*. " Microtubule-Targeted Self-Assembly Triggers Prometaphase-Metaphase Oscillations Suppressing Tumor Growth" Nano Letters, 2021, 21, 3052-3059. (+ These authors contributed equally to this work). 


  4. Chengzhi Jin, Guanying Li, Xia Wu, Jiangpin Liu, Weijun Wu, Yazhou chen, Toshio Sasaki, Hui Chao,* and Ye Zhang.* "Robust Packing of Self-Assembling Iridium Complex via Endocytic Trafficking for Long-Term Lysosome Tracking" Angew. Chem. Int. Ed. 2021, 60, 7597-7601.


  5. Guanying Li, Xunwu Hu, Pingping Nie, Dingze Mang, Shi Jiao, Shijin Zhang, Sona Roy, Sachie Yukawa, Shunsuke Asahina, Hiroaki Sugasawa, William Cortes, Zhaocai Zhou,* and Ye Zhang.* "Lipid-raft-targeted Molecular Self-assembly Inactivates YAP to Treat Ovarian Cancer" Nano Letters, 2021, 21, 747-755.


  6. Xia Wu, Xunwu Hu, and Ye Zhang.* "Regulate Cellular Responses via Molecular Assembly in Cell Milieu for Cancer Therapy" (Highlight Review) Chemistry Letters, 2021, 50, 405-410.


  7. Guanying Li, William Cortes, Qizheng Zhang, and Ye Zhang.* "Chemical Oscillation and Morphological Oscillation in Catalyst-embedded Lyotropic Liquid Cristalline Gels" Frontiers in Chemistry, 2020,


  8. Shijin Zhang, and Ye Zhang.* "Promote Dual-Targeting Anticancer Effect by Regulating the Dynamic Intracellular Self-Assembly" ACS Applied Materials & Interfaces, 2020, 12, 37, 41105-41112.


  9. Jiaqing Wang, Weiyi Tan, Guanying Li, Difei Wu, Hongjian He, Jiashu Xu, Meihui Yi, Ye Zhang, S. Ali Aghvami, Seth Fraden, Bing Xu.* "Enzymatic Insertion of Lipids Increases Membrane Tension for Inhibiting Cancer Cells" Chem. Eur. J. 2020,

  10. Shijin Zhang, William Cortes, and Ye Zhang.* "Constructing Cross-linked Nanofibrous Scaffold via Dual-Enzyme-Instructed Hierarchical AssemblyLangmuir, 2020, 36, 6261-6267.


  11. Sona Rani Roy, Guanying Li, Xunwu Hu, Shijin Zhang, Sachie Yukawa, Enming Du, and Ye Zhang.* "Integrin and Heparan Sulfate Dual-tageting Peptide Assembly Suppresses Cancer Metastasis" ACS Applied Materials & Interfaces, 2020, 17, 19277-19284.                                                     

  12. Dingze Mang,+ Sona Rani Roy,+ Hong Huat Hoh, Xia Wu, Jiahao Zhang, Chengzhi Jin, and Ye Zhang.* "Self-Assembly of Integrin Ligands on the Apical Membrane Inhibits the Migration of Glioma CellsLangmuir2020, 14, 3750-3757. (+ These authors contribute equally to this work).


  13. Shijin Zhang1,+, William Cortes1,+, Toshio Sasaki2, Shunsuke Asahina3, Asano Natsuko3, Qizheng Zhang1, and Ye Zhang.1,* "Mechanoresponsive Alignment of Molecular Self-assembled Negatively Charged NanofibrilsACS Applied Bio Materials. 2020, 3, 1698-1704 (+These authors contribute equally to this work).



  1. Shijin Zhang, Xunwu Hu, Dingze Mang, Toshio Sasaki, and Ye Zhang.* "Self-delivery of N-hydroxylethyl Peptide Assemblies to the Cytosol Inducing Endoplasmic Reticulum Dilation in Cancer Cells Chem. Commun. 2019, 55, 7474-7477.

  2. Dingze Mang,+ Shijin Zhang,+ Xia Wu, Toshiaki Mochizuki, Guanying Li, and Ye Zhang.* "Enzyme-mediated dual-targeted-assembly realizes a synergistic anticancer effect" Chem. Commun. 2019, 55, 6126 - 6129  (+These authors contribute equally to this work)


  1. Enming Du, Xunwu Hu, Guanying Li, Shijin Zhang, Dingze Mang, Sona Roy, Toshio Sasaki, and Ye Zhang.* "Self-assembly-Directed Cancer Cell Membrane Insertion of Synthetic Ananlogues for Permeability Alteration" Langmuir2019, 35, 7376 - 7382.


  2. Wei Ji, Shijin Zhang, Sachie Yukawa, Shogo Onomura, Toshio Sasaki, Kun'ichi Miyazawa, and Ye Zhang.* "Regulate  Higher-order Organization through the Synergy of Two Self-sorted Assemblies" Angew. Chem. Int. Ed. 2018, 57, 3636-3640


  1. Enming Du, Xunwu Hu, Sona Roy, Peng Wang, Kieran Deasy, Toshiaki Mochizuki and Ye Zhang.* "Taurine-Modified Ru(II)-Complex Targets Cancerous Brain Cells for Photodynamic Therapy" Chem. Commun. 2017, 53, 6033-6036


  2. Wei Ji, Shijin Zhang, Gerogy A. Filonenko, Guanying Li, Toshio Sasaki, Chuanliang Feng* and Ye Zhang.* "Co-Organizing Synthesis of Heterogeneous Nanostructure through Photo-Cleavage of Pre-Stabilized Self-Assemblies" Chem. Commun. 2017, 53, 4702-4705.


  3. Guanying Li, Toshio Sasaki, Shunsuke Asahina, Michael C. Roy, Toshiaki Mochizuki, Koji Koizumi  and Ye Zhang.* “Patching of Lipid Rafts by Molecular Self-Assembled Nanofibrils Suppresses Cancer Cell Migration” Chem2017, 2, 283-298.


  1. Yunhui Zheng, Guanying Li and Ye Zhang.* "Organometallic Hydrogels" ChemNanoMat, 2016, 2, 364-375.

  2. Qingcong Wei, Mengchi Xu, Chuanan Liao, Qing Wu, Mingyu Liu, Ye Zhang,* Chengtie Wu,* Liming Cheng and Qigang Wang.*  "Printable hybrid hydrogel by dual enzymatic polymerization with superactivity" Chemical Science, 2016, 7, 2748.

Before moving to OIST

  1. Zhang, Y.; Zhou, N.; Shi, J. F.; Pochapsky, S. S.; Pochapsky, T. C.; Zhang, B.; Zhang, X. X.; Xu, B.* “Unfolding a molecular trefoil derived from a zwitterionic metallopeptide to form self-assembled nanostructures” Nature Commun. 2015, 6, 6165.
  2. Shi, J. F.; Du, X. W.; Huang, Y. B.; Zhou, J.; Yuan, D.; Wu, D. D.; Zhang, Y.; Haburcak, R.; Eptein, I. R.*; Xu, B.* “Ligand-Receptor Interaction Catalyzes the Aggregation of Small Molecules to Induce Cell Necroptosis” J. Am. Chem. Soc. 2015, 137, 26.
  3. Park, S.; Kim, D.; Ko, S. Y.; Park, J-O., Akella S., Xu, B., Zhang, Y.; Fraden, S.* “Controlling uniformity of photo-polymerized microscopic hydrogels” Lab on a Chip. 2014, 14, 1551-1563.
  4. Zhang, Y.; Zhou, N.; Kim, D.; Fraden, S.*; Epstein, I. R.*; Xu, B.* “ Giant Volume Change of Active Gels under Continuous Flow” J. Am. Chem. Soc., 2014, 136, 7341-7347.
  5. Zhang, Y.; Zhou, N.; Akella, S.; Kuang, Y.; Kim, D.; Schwartz, A.; Bezpalko, M.; Foxman, B. M.; Fraden, S.; Epstein, I. R.*; Xu, B.* “ Active Hyper Crosslinkers Confer Active Gels” Angew. Chem. Int. Ed. 2013, 52, 6944-6948.
  6. Zhang, Y.; Zhou, R.; Shi, J.; Zhou, N.; Epstein, I. R.; Xu, B.* “Post-Self-Assembly Cross-Linking to Integrate Molecular Nanofibers with Copolymers in Oscillatory Hydrogels” J. Phys. Chem. B, 2013, 117, 6566-6573.
  7. Zhang, Y.; Zhang, B.; Kuang, Y.; Gao, Y.; Shi, J.; Zhang, X. X.; Xu, B.* “A Redox Responsive, Fluorescent Supramolecular Metallohydrogel Consists of Nanofibers with Single-Molecule Width” J. Am. Chem. Soc., 2013, 135, 5008-5011.
  8. Kuang, Yi.; Yuan, D.; Zhang, Y.; Du, X. W.; Xu, B.* “Interactions between cellular proteins and morphologically different nanoscale aggregates of small molecules” RSC Advances, 2013, 3, 7704-7707.
  9. Yang, Z. M.; Kuang, Y.; Li, X. M.; Zhou, N.; Zhang, Y.; Xu, B.* “Supramolecular hydrogel of kanamycin selectively sequesters 16S rRNA” Chem. Commun. 2012, 48, 9257-9259.
  10. Zhang, Y.; Li, N.; Delgado, J.; Zhou, N.; Yoshida, R.; Fraden, S.; Epstein, I. R.*; Xu, B.* “Structural modulation of self-oscillating gels: Changing the proximity of the catalyst to the polymer backbone to tailor chemomechanical oscillation” Soft Matter, 2012, 8, 7056-7061.
  11. Zhang, Y.; Li, N.; Delgado, J.; Gao, Y.; Kuang, Y.; Fraden, S.; Epstein, I. R.*; Xu, B.* “Post-Self-Assembly Crosslinking of Molecular Nanofibers for Oscillatory Hydrogels” Langmuir, 2012, 28, 3063-3066.
  12. Zhang, Y.; Xu, B. “Multifunctional Magnetic Nanoparticles as Bionanomaterials” American Institute of Biological Sciences, 2011, July.
  13. Delgado, J.; Zhang, Y.; Xu, B.; Epstein, I. R. “Terpyridine- and Bipyridine-Based Ruthenium Complexes as Catalysts for the Belousov-Zhabotinsky Reaction” J. Phys. Chem. A, 2011, 115, 2208-2215.
  14. Shi, J. F.; Gao, Y.; Zhang, Y.; Pan, Y.; Xu, B.* “Calcium Ions to Crosslink Supramolecular Nanofibers to Tune the Elasticity of Hydrogels over Orders of Magnitude” Langmuir, 2011, 27, 14425-14431.
  15. Zhang, Y.; Yousef, Y. A.; Li, H.; Melø, T. B.; Naqvi, K. R.* “Comparison of the photochemical behaviors of α-tocopherol and its acetate in organic and aqueous micellar solutions” J. Phy. Chem. A. 2011, 29, 8242-8247.
  16. Zhang, Y.; Kuang, Y.; Gao, Y.; Xu, B.* “Versatile Small Molecule Motifs for Self-assembly in Water and Formation of Biofunctional Supramolecular Hydrogels” Langmuir, 2011, 27, 529-537.
  17. Gao, Y.; Zhao, F.; Wang, Q. G.; Zhang, Y.; Xu, B.* “Small Peptide Nanofibers as the Matrices of Molecular Hydrogels for Mimicking Enzymes and Enhancing the Activity of Enzymes” Chem. Soc. Rev. 2010, 39, 3425-3433.
  18. Dai, W-M.*; Li, Y.; Zhang, Y.; Yue, C.; Wu, J. “Generation of an Aromatic Amide-Derived Phosphane (Aphos) Library by Self-Assisted Molecular Editing and Applications of Aphos in Room-Temperature Suzuki-Miyaura Reactions” Chem. Eur. J. 2008, 14, 5538-5554.
  19. Dai, W-M.*; Zhang, Y. “A Family of Simple Amide-Derived Air-Stable P,O-Ligands for Suzuki Cross-Coupling of Unactivated Aryl Chlorides” Tetrahedron Lett. 2005, 46, 1377-1381.
  20. Dai, W-M.*; Li, Y.; Zhang, Y.; Lai, K. W.; Wu, J. “A Novel Class of Amide-Derived Air-Stable P,O-Ligands for Suzuki Cross-Coupling at Low Catalyst Loading” Tetrahedron Lett. 2004, 45, 1999-2001.
  21. Dai. W-M.*; Zhang, Y.; Zhang, Y. “Synthesis of Atropisomeric 2,8-Dioxygenated N,N-Diisopropyl-1-naphthamides via Kinetic Resolution under the Sharpless Asymmetric Dihydroxylation Conditions” Tetrahedron: Asymmetry 2004, 15-525-535.
  22. Dai, W-M.*; Yeung, K. Y.; Liu, J-T.; Zhang, Y.; Williams, I. D. “A Novel Class of Nonbiaryl Atropisomeric P,O-Ligands for Palladium-Catalyzed Asymmetric Allylic Alkyation” Org. Lett. 2002, 4, 1615-1618.